Sesquiterpenes with anti-inflammatory activity from the stems and branches of Melicope patulinervia
文献类型：期刊论文
| 作者 | Li, Sai3,4; Du, En-Lian3,4; Gong, Qi2; Chen, Fei1,3; Tan, Jun-Jie3 ; Qu, Shi-Jin3; Zhang, Hai-Yan1,2; Tan, Chang-Heng1,3,4
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| 刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
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| 出版日期 | 2025-07-03 |
| 卷号 | 27期号:7页码:977-982 |
| 关键词 | |
| ISSN号 | 1028-6020 |
| DOI | 10.1080/10286020.2025.2508874 |
| 英文摘要 | Five new sesquiterpenes comprising three zieranes, melicopatulones A-C (1-3) and two guaianes, melicopatulones D-E (5-6), were isolated from the stems and branches of Melicope patulinervia, together with melicodenones B (4), C (7) and D (8). Their structures with absolute configurations were elucidated on the basis of analysis of MS, NMR, and TDDFT-ECD calculations. Sesquiterpenes 1, 2 and 6 exhibited significant inhibitory effect at 10 mu M on lipopolysaccharide-induced NO production in BV-2 microglial cells. |
| WOS关键词 | A-C ; PTELEIFOLIA ; LIGNANS ; LEAVES |
| 资助项目 | National Science & Technology Major Project Key New Drug Creation and Manufacturing Program of the National Health Commission of China[2019ZX09201001] |
| WOS研究方向 | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:001498175400001 |
| 出版者 | TAYLOR & FRANCIS LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/318201]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Zhang, Hai-Yan; Tan, Chang-Heng |
| 作者单位 | 1.Univ Chinese Acad Sci, Sch Pharm, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Chem Biol, State Key Lab Drug Res, Shanghai 201203, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, Nat Prod Res Ctr, Shanghai 201203, Peoples R China 4.Nanjing Univ Chinese Med, Sch Chinese Mat Med, Nanjing 210023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Sai,Du, En-Lian,Gong, Qi,et al. Sesquiterpenes with anti-inflammatory activity from the stems and branches of Melicope patulinervia[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2025,27(7):977-982. |
| APA | Li, Sai.,Du, En-Lian.,Gong, Qi.,Chen, Fei.,Tan, Jun-Jie.,...&Tan, Chang-Heng.(2025).Sesquiterpenes with anti-inflammatory activity from the stems and branches of Melicope patulinervia.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,27(7),977-982. |
| MLA | Li, Sai,et al."Sesquiterpenes with anti-inflammatory activity from the stems and branches of Melicope patulinervia".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 27.7(2025):977-982. |
入库方式： OAI收割
来源：上海药物研究所
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