Triconnarins A-D: Four Secophragmalin-Type Limonoids from the Twigs and Leaves of Trichilia connaroides
文献类型：期刊论文
| 作者 | Xu, Jia-Xin2; Zhao, Hai-Yang2; Li, Xiao-Zhou2; Li, Zhi-Ying2; Shen, Tao2; Ren, Dong-Mei2; Yue, Jian-Min1,2 ; Wang, Xiao-Ning2
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| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2025-06-16 |
| 卷号 | 27期号:25页码:6772-6776 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/acs.orglett.4c04459 |
| 英文摘要 | Four novel secophragmalin-type limonoids, triconnarins A-D (1-4), have been identified from the small branches and leaves of Trichilia connaroides. Triconnarin A (1) featured an unprecedented 5/6/4/6/6 ring skeleton, which belonged to the rare 1,10-secophragmalin classes. Triconnarin B (2) was the first B-ring opening secophragmalin limonoid, whereas triconnarin C (3) possessed a unique 5/5-6/6 ring system. Compounds 1-3 were proven to demonstrate potent QR-inducing activity. |
| 资助项目 | National Natural Science Foundation of China[21877071] ; National Natural Science Foundation of China |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001514094200001 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/318480]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Yue, Jian-Min; Wang, Xiao-Ning |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 2.Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Key Lab Chem Biol,Minist Educ, Jinan 250012, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Jia-Xin,Zhao, Hai-Yang,Li, Xiao-Zhou,et al. Triconnarins A-D: Four Secophragmalin-Type Limonoids from the Twigs and Leaves of Trichilia connaroides[J]. ORGANIC LETTERS,2025,27(25):6772-6776. |
| APA | Xu, Jia-Xin.,Zhao, Hai-Yang.,Li, Xiao-Zhou.,Li, Zhi-Ying.,Shen, Tao.,...&Wang, Xiao-Ning.(2025).Triconnarins A-D: Four Secophragmalin-Type Limonoids from the Twigs and Leaves of Trichilia connaroides.ORGANIC LETTERS,27(25),6772-6776. |
| MLA | Xu, Jia-Xin,et al."Triconnarins A-D: Four Secophragmalin-Type Limonoids from the Twigs and Leaves of Trichilia connaroides".ORGANIC LETTERS 27.25(2025):6772-6776. |
入库方式： OAI收割
来源：上海药物研究所
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