Protein and Peptide-Based Nanotechnology for Enhancing Stability, Bioactivity, and Delivery of Anthocyanins
文献类型：期刊论文
| 作者 | Zhang, Lei1,2; Yao, Liang3; Zhao, Feng1,2; Yu, Alice4; Zhou, Yueru1,2; Wen, Qingmei5; Wang, Jun3; Zheng, Tao5; Chen, Pu1,2 |
| 刊名 | ADVANCED HEALTHCARE MATERIALS
 |
| 出版日期 | 2023-08-03 |
| 页码 | 31 |
| 关键词 | anthocyanin bioactivity delivery nanotechnology peptide protein stability |
| ISSN号 | 2192-2640 |
| DOI | 10.1002/adhm.202300473 |
| 通讯作者 | Zhang, Lei(l78zhang@uwaterloo.ca) ; Chen, Pu(p4chen@uwaterloo.ca) |
| 英文摘要 | Anthocyanin, a unique natural polyphenol, is abundant in plants and widely utilized in biomedicine, cosmetics, and the food industry due to its excellent antioxidant, anticancer, antiaging, antimicrobial, and anti-inflammatory properties. However, the degradation of anthocyanin in an extreme environment, such as alkali pH, high temperatures, and metal ions, limits its physiochemical stabilities and bioavailabilities. Encapsulation and combining anthocyanin with biomaterials could efficiently stabilize anthocyanin for protection. Promisingly, natural or artificially designed proteins and peptides with favorable stabilities, excellent biocapacity, and wide sources are potential candidates to stabilize anthocyanin. This review focuses on recent progress, strategies, and perspectives on protein and peptide for anthocyanin functionalization and delivery, i.e., formulation technologies, physicochemical stability enhancement, cellular uptake, bioavailabilities, and biological activities development. Interestingly, due to the simplicity and diversity of peptide structure, the interaction mechanisms between peptide and anthocyanin could be illustrated. This work sheds light on the mechanism of protein/peptide-anthocyanin nanoparticle construction and expands on potential applications of anthocyanin in nutrition and biomedicine. |
| WOS关键词 | SELF-ASSEMBLING PEPTIDE ; WHEY-PROTEIN ; AMINO-ACID ; THERMAL-STABILITY ; PLANT PROTEIN ; FOOD SYSTEMS ; IN-VITRO ; PHYSICOCHEMICAL PROPERTIES ; PRODUCTION TECHNOLOGIES ; BLUEBERRY ANTHOCYANINS |
| 资助项目 | Mitacs Fellowship (Canada)[IT18262] |
| WOS研究方向 | Engineering ; Science & Technology - Other Topics ; Materials Science |
| 语种 | 英语 |
| WOS记录号 | WOS:001040078200001 |
| 出版者 | WILEY |
| 资助机构 | Mitacs Fellowship (Canada) |
| 源URL | [http://ir.giec.ac.cn/handle/344007/39279]  |
| 专题 | 中国科学院广州能源研究所 |
| 通讯作者 | Zhang, Lei; Chen, Pu |
| 作者单位 | 1.Univ Waterloo, Dept Chem Engn, Waterloo, ON N2L3G1, Canada 2.Waterloo Inst Nanotechnol Univ Waterloo, Waterloo, ON N2L3G1, Canada 3.Jiangsu Univ Sci & Technol, Sericultural Res Inst, Coll Biotechnol, Zhenjiang 212018, Jiangsu, Peoples R China 4.Western Univ, Schulich Sch Med & Dent, London, ON N6A 3K7, Canada 5.Chinese Acad Sci, Guangzhou Inst Energy Convers, Guangzhou 510640, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Lei,Yao, Liang,Zhao, Feng,et al. Protein and Peptide-Based Nanotechnology for Enhancing Stability, Bioactivity, and Delivery of Anthocyanins[J]. ADVANCED HEALTHCARE MATERIALS,2023:31. |
| APA | Zhang, Lei.,Yao, Liang.,Zhao, Feng.,Yu, Alice.,Zhou, Yueru.,...&Chen, Pu.(2023).Protein and Peptide-Based Nanotechnology for Enhancing Stability, Bioactivity, and Delivery of Anthocyanins.ADVANCED HEALTHCARE MATERIALS,31. |
| MLA | Zhang, Lei,et al."Protein and Peptide-Based Nanotechnology for Enhancing Stability, Bioactivity, and Delivery of Anthocyanins".ADVANCED HEALTHCARE MATERIALS (2023):31. |
入库方式： OAI收割
来源：广州能源研究所
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