The identification of apolipoprotein C-I in rare minnow (Gobiocypris rarus) and its expression following cadmium exposure
文献类型：期刊论文
| 作者 | Wang, Chunling1,2,3; Zhang, Futie1,2; Cao, Wenxuan1,2; Wang, Jianwei1,2 |
| 刊名 | ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
 |
| 出版日期 | 2013-05-01 |
| 卷号 | 35期号:3页码:419-426 |
| 关键词 | Apolipoprotein C-I Cadmium Gene expression Rare minnow |
| ISSN号 | 1382-6689 |
| 通讯作者 | Zhang, FT (reprint author), Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Hubei Province, Peoples R China. |
| 中文摘要 | Cadmium (Cd) is a ubiquitous environment contaminant that has been detected in a variety of terrestrial and aquatic organisms. In our study, rare minnow were exposed to 0.4 mg/L Cd2+ solution, fish tissues including gill, intestine, kidney, liver, muscle, and spleen were collected at 1, 6, 12,24 and 48 h after exposure. Differential expression sequence tags (ESTs) were screened and an EST similar to Hemibarbus mylodon apolipoprotein C-I (ApoC-I) was identified. The ApoC-I cDNA had been obtained with the sequence of 583 bp, which can code 84 amino acids. The transcription expression patterns of ApoC-I were compared after Cd exposure with the real-time PCR in the above tissues. ApoC-I regulation was prominent in spleen, muscle, gill and liver and moderate in kidney and intestine. This suggests a complex transcriptional regulation of ApoC-I expression following Cd exposure. (c) 2013 Elsevier B.V. All rights reserved. |
| 英文摘要 | Cadmium (Cd) is a ubiquitous environment contaminant that has been detected in a variety of terrestrial and aquatic organisms. In our study, rare minnow were exposed to 0.4 mg/L Cd2+ solution, fish tissues including gill, intestine, kidney, liver, muscle, and spleen were collected at 1, 6, 12,24 and 48 h after exposure. Differential expression sequence tags (ESTs) were screened and an EST similar to Hemibarbus mylodon apolipoprotein C-I (ApoC-I) was identified. The ApoC-I cDNA had been obtained with the sequence of 583 bp, which can code 84 amino acids. The transcription expression patterns of ApoC-I were compared after Cd exposure with the real-time PCR in the above tissues. ApoC-I regulation was prominent in spleen, muscle, gill and liver and moderate in kidney and intestine. This suggests a complex transcriptional regulation of ApoC-I expression following Cd exposure. (c) 2013 Elsevier B.V. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Environmental Sciences ; Pharmacology & Pharmacy ; Toxicology |
| 研究领域[WOS] | Environmental Sciences & Ecology ; Pharmacology & Pharmacy ; Toxicology |
| 关键词[WOS] | PERFLUOROOCTANOIC ACID ; SYNECHOGOBIUS-HASTA ; MOLECULAR-CLONING ; MULTIGENE FAMILY ; OXIDATIVE STRESS ; FISH ; RESPONSES ; GENE ; ACCUMULATION ; VITELLOGENIN |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China [30900154]; Knowledge Innovation Program of the Chinese Academy of Sciences [Y15E011101]; National 863 High Technology Research Program of China [2012AA06A302-4] |
| 语种 | 英语 |
| WOS记录号 | WOS:000317943500008 |
| 公开日期 | 2013-10-31 |
| 源URL | [http://ir.ihb.ac.cn/handle/342005/19258]  |
| 专题 | 水生生物研究所_水生生物多样性与资源保护研究中心_期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Hubei Province, Peoples R China 2.Chinese Acad Sci, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Hubei Province, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Chunling,Zhang, Futie,Cao, Wenxuan,et al. The identification of apolipoprotein C-I in rare minnow (Gobiocypris rarus) and its expression following cadmium exposure[J]. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,2013,35(3):419-426. |
| APA | Wang, Chunling,Zhang, Futie,Cao, Wenxuan,&Wang, Jianwei.(2013).The identification of apolipoprotein C-I in rare minnow (Gobiocypris rarus) and its expression following cadmium exposure.ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,35(3),419-426. |
| MLA | Wang, Chunling,et al."The identification of apolipoprotein C-I in rare minnow (Gobiocypris rarus) and its expression following cadmium exposure".ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 35.3(2013):419-426. |
入库方式： OAI收割
来源：水生生物研究所
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