Preliminary Study of the Distribution and Accumulation of GSH/Cys Metabolites of Hepatotoxic Microcystins-RR in Common Carp from a Lake with Protracted Cyanobacterial Bloom (Lake Taihu, China)
文献类型：期刊论文
| 作者 | Wu, Laiyan1,2,3; Wang, Qing1; Tao, Min1; Chen, Jun1; Ma, Zhimei1; Xie, Ping1 |
| 刊名 | BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
 |
| 出版日期 | 2013-03-01 |
| 卷号 | 90期号:3页码:382-386 |
| 关键词 | MC-RR-GSH MC-RR-Cys Common carp LC-MS Risk assessment |
| ISSN号 | 0007-4861 |
| 通讯作者 | Xie, P (reprint author), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Donghu South Rd 7th, Wuhan 430072, Peoples R China. |
| 中文摘要 | Tissue distributions and seasonal dynamics of glutathione and cysteine S-conjugates of microcystin-RR in feral fish from Lake Taihu were studied. High MC-RR-Cys was found in tissues, Mean MC-RR-Cys in kidney (0.253 mu g g(-1) DW) was 4 times of that in liver (0.063 mu g g(-1) DW). Ratios of MC-RR-Cys/MC-RR in liver/kidney reached as high as 5.3/39.8, respectively, meanwhile, kidney showed low accumulation of MC-RR and higher formation efficiency of MC-RR-Cys than liver (7.51x to liver), this suggested that MC-RR-Cys were significantly accumulated with the depletion of MC-RR, and it was selectively biotransformed to MC-RR-Cys in kidney for further excretion. |
| 英文摘要 | Tissue distributions and seasonal dynamics of glutathione and cysteine S-conjugates of microcystin-RR in feral fish from Lake Taihu were studied. High MC-RR-Cys was found in tissues, Mean MC-RR-Cys in kidney (0.253 mu g g(-1) DW) was 4 times of that in liver (0.063 mu g g(-1) DW). Ratios of MC-RR-Cys/MC-RR in liver/kidney reached as high as 5.3/39.8, respectively, meanwhile, kidney showed low accumulation of MC-RR and higher formation efficiency of MC-RR-Cys than liver (7.51x to liver), this suggested that MC-RR-Cys were significantly accumulated with the depletion of MC-RR, and it was selectively biotransformed to MC-RR-Cys in kidney for further excretion. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Environmental Sciences ; Toxicology |
| 研究领域[WOS] | Environmental Sciences & Ecology ; Toxicology |
| 关键词[WOS] | GLUTATHIONE ; FISH ; LR ; IDENTIFICATION ; CONJUGATE ; TOXICITY ; DYNAMICS |
| 收录类别 | SCI |
| 资助信息 | Fundamental Research Funds for the Central Universities; South Central University for Nationalities [CZQ11023]; Chinese Academy of Science [KZCX1-YW-14-6-1]; National Basic Research Program of China (973 Program) [2008CB418101] |
| 语种 | 英语 |
| WOS记录号 | WOS:000316002700021 |
| 公开日期 | 2013-10-31 |
| 源URL | [http://ir.ihb.ac.cn/handle/342005/19291]  |
| 专题 | 水生生物研究所_淡水生态学研究中心_期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol China, Donghu Expt Stn Lake Ecosyst, Wuhan 430072, Peoples R China 2.South Cent Univ Nationality, Inst Environm Engn & Sci, Key Lab Catalysis & Mat Sci, State Ethn Affairs Commiss, Wuhan 430074, Peoples R China 3.South Cent Univ Nationality, Inst Environm Engn & Sci, Minist Educ Chem & Mat Sci, Wuhan 430074, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Laiyan,Wang, Qing,Tao, Min,et al. Preliminary Study of the Distribution and Accumulation of GSH/Cys Metabolites of Hepatotoxic Microcystins-RR in Common Carp from a Lake with Protracted Cyanobacterial Bloom (Lake Taihu, China)[J]. BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY,2013,90(3):382-386. |
| APA | Wu, Laiyan,Wang, Qing,Tao, Min,Chen, Jun,Ma, Zhimei,&Xie, Ping.(2013).Preliminary Study of the Distribution and Accumulation of GSH/Cys Metabolites of Hepatotoxic Microcystins-RR in Common Carp from a Lake with Protracted Cyanobacterial Bloom (Lake Taihu, China).BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY,90(3),382-386. |
| MLA | Wu, Laiyan,et al."Preliminary Study of the Distribution and Accumulation of GSH/Cys Metabolites of Hepatotoxic Microcystins-RR in Common Carp from a Lake with Protracted Cyanobacterial Bloom (Lake Taihu, China)".BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 90.3(2013):382-386. |
入库方式： OAI收割
来源：水生生物研究所
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