Cryosphere: a frozen home of microbes and a potential source for drug discovery
文献类型：期刊论文
| 作者 | Zada, Sahib1; Khan, Mohsin2; Su, Zheng1; Sajjad, Wasim3; Rafiq, Muhammad4 |
| 刊名 | ARCHIVES OF MICROBIOLOGY
 |
| 出版日期 | 2024-04-01 |
| 卷号 | 206期号:4页码:23 |
| 关键词 | Cryosphere Drug discovery Antimicrobial compounds Novel microbes Antibiotic resistance |
| ISSN号 | 0302-8933 |
| DOI | 10.1007/s00203-024-03899-4 |
| 通讯作者 | Sajjad, Wasim(wasim.sajjad71@yahoo.com) ; Rafiq, Muhammad(mr14311@my.bristol.ac.uk) |
| 英文摘要 | The world is concerned about the emergence of pathogens and the occurrence and spread of antibiotic resistance among pathogens. Drug development requires time to combat these issues. Consequently, drug development from natural sources is unavoidable. Cryosphere represents a gigantic source of microbes that could be the bioprospecting source of natural products with unique scaffolds as molecules or drug templates. This review focuses on the novel source of drug discovery and cryospheric environments as a potential source for microbial metabolites having potential medicinal applications. Furthermore, the problems encountered in discovering metabolites from cold-adapted microbes and their resolutions are discussed. By adopting modern practical approaches, the discovery of bioactive compounds might fulfill the demand for new drug development. |
| WOS关键词 | PEPTIDE DEFORMYLASE INHIBITORS ; HIMALAYAN MOUNTAIN-RANGES ; SP-NOV. ; ANTIBIOTIC-RESISTANCE ; BACTERIAL COMMUNITIES ; CULTURABLE BACTERIA ; CRYOCONITE HOLES ; ANTIMICROBIAL ACTIVITY ; BACILLUS-SUBTILIS ; HAMTA GLACIER |
| 资助项目 | Gansu Provincial Science and Technology Program ; Guangzhou Institute of Energy Conservation, Chinese Academy of Sciences ; [22ZD6FA005] |
| WOS研究方向 | Microbiology |
| 语种 | 英语 |
| WOS记录号 | WOS:001195452400002 |
| 出版者 | SPRINGER |
| 资助机构 | Gansu Provincial Science and Technology Program ; Guangzhou Institute of Energy Conservation, Chinese Academy of Sciences |
| 源URL | [http://ir.giec.ac.cn/handle/344007/41363]  |
| 专题 | 中国科学院广州能源研究所 |
| 通讯作者 | Sajjad, Wasim; Rafiq, Muhammad |
| 作者单位 | 1.Chinese Acad Sci, Guangzhou Inst Energy Convers, Guangzhou, Peoples R China 2.Ohio Univ, Dept Biol Sci, Athens, OH USA 3.Chinese Acad Sci, Northwest Inst Ecoenvironm & Resources, State Key Lab Cryospher Sci, Lanzhou 730000, Peoples R China 4.Balochistan Univ IT Engn & Management Sci, Fac Life Sci & Informat, Dept Microbiol, Quetta 87650, Pakistan |
| 推荐引用方式 GB/T 7714 | Zada, Sahib,Khan, Mohsin,Su, Zheng,et al. Cryosphere: a frozen home of microbes and a potential source for drug discovery[J]. ARCHIVES OF MICROBIOLOGY,2024,206(4):23. |
| APA | Zada, Sahib,Khan, Mohsin,Su, Zheng,Sajjad, Wasim,&Rafiq, Muhammad.(2024).Cryosphere: a frozen home of microbes and a potential source for drug discovery.ARCHIVES OF MICROBIOLOGY,206(4),23. |
| MLA | Zada, Sahib,et al."Cryosphere: a frozen home of microbes and a potential source for drug discovery".ARCHIVES OF MICROBIOLOGY 206.4(2024):23. |
入库方式： OAI收割
来源：广州能源研究所
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