Advance of the application of seaweed polysaccharides on antitumor drug delivery systems
文献类型：期刊论文
| 作者 | Yin, Xiaofei2,4,5; Geng, Xinrong2,4,5; Li, Wenjun2,4,5; Che, Tuanjie1,5; Yan, Libo1,5; Yuan, Biao3; Qin, Song2,4,5 |
| 刊名 | INTERNATIONAL JOURNAL OF PHARMACEUTICS
 |
| 出版日期 | 2025-04-30 |
| 卷号 | 675页码:14 |
| 关键词 | Oncology therapy Alginate Carrageenan Fucoidan Drug delivery Polysaccharides |
| ISSN号 | 0378-5173 |
| DOI | 10.1016/j.ijpharm.2025.125502 |
| 通讯作者 | Yuan, Biao(yuanbiao@cpu.edu.cn) ; Qin, Song(sqin@yic.ac.cn) |
| 英文摘要 | In recent years, the morbidity and death rate of patients with tumors have been continuously increasing. How to administer radiotherapy, chemotherapy, and other methods for reducing damage to normal tissue cells and accurately targeting the tumor is one of the key issues in solving the problem of cancer. Using nanocarriers is a feasible approach into targeted control on the release of medicine to increase patient compliance. Nowadays, many researchers are gradually focusing on the application of drug delivery systems with natural ingredients as carriers in tumor therapy. At the same time, natural active ingredients may have better biocompatibility and fewer side effects. Especially, a variety of polysaccharides from algae has exhibited antitumor activity, providing greater possibilities for their use as drug delivery carriers. To facilitate the advancement and clinical translation of algae-derived polysaccharides in medical applications, we summarized the structural features of a range of polysaccharides extracted from macroalgae, their physical properties suitable for use as carriers, and the ways they are utilized in delivering medicines in oncology therapy (particularly in combination with novel oncology therapies, such as immunotherapy and photothermal therapy). |
| WOS关键词 | CANCER-TREATMENT ; TUMOR MICROENVIRONMENT ; PHOTOTHERMAL THERAPY ; CO-DELIVERY ; NANOPARTICLES ; FUCOIDAN ; CARRAGEENAN ; DOXORUBICIN ; HYDROGELS ; CURCUMIN |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:001464535400001 |
| 资助机构 | National Key Research and Devel-opment Program of China |
| 源URL | [http://ir.yic.ac.cn/handle/133337/40858]  |
| 专题 | 海岸带生物学与生物资源利用重点实验室 |
| 通讯作者 | Yuan, Biao; Qin, Song |
| 作者单位 | 1.Zhigong Biomed Co Ltd, Yantai 2640035, Shandong, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Shandong, Peoples R China 3.China Pharmaceut Univ, Coll Engn, Natl R&D Ctr Chinese Herbal Med Proc, Dept Food Qual & Safety, Nanjing 211198, Jiangsu, Peoples R China 4.Shandong Univ Tradit Chinese Med, Res Inst Marine Tradit Chinese Med, Qingdao 266112, Shandong, Peoples R China 5.Yantai Ctr Technol Innovat Coastal Zone Biol Resou, Yantai, Shandong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yin, Xiaofei,Geng, Xinrong,Li, Wenjun,et al. Advance of the application of seaweed polysaccharides on antitumor drug delivery systems[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS,2025,675:14. |
| APA | Yin, Xiaofei.,Geng, Xinrong.,Li, Wenjun.,Che, Tuanjie.,Yan, Libo.,...&Qin, Song.(2025).Advance of the application of seaweed polysaccharides on antitumor drug delivery systems.INTERNATIONAL JOURNAL OF PHARMACEUTICS,675,14. |
| MLA | Yin, Xiaofei,et al."Advance of the application of seaweed polysaccharides on antitumor drug delivery systems".INTERNATIONAL JOURNAL OF PHARMACEUTICS 675(2025):14. |
入库方式： OAI收割
来源：烟台海岸带研究所
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