A molecularly imprinted polymer-based triple-ratio fluorescence nanosensor integrated with a paper-based microfluidic chip for rapid detection of enoxacin
文献类型：期刊论文
| 作者 | Wang, Chao2; Wen, Yuhao1; Wang, Siyu4; Xiang, Jiawen3; Hu, Die3; Man, Mingsan3; Zhang, Xin4; Li, Bowei3; Chen, Lingxin3 |
| 刊名 | TALANTA
 |
| 出版日期 | 2025-12-01 |
| 卷号 | 295页码:12 |
| 关键词 | Enoxacin Molecularly imprinted materials Triple-ratios fluorescence nanosensor Paper-based microfluidic chip |
| ISSN号 | 0039-9140 |
| DOI | 10.1016/j.talanta.2025.128343 |
| 通讯作者 | Zhang, Xin(xzhang@qdio.ac.cn) ; Li, Bowei(bwli@yic.ac.cn) ; Chen, Lingxin(lxchen@yic.ac.cn) |
| 英文摘要 | Enoxacin (ENX), a commonly used fluoroquinolone antibiotic, has raised environmental concerns due to its widespread use and resulting pollution. This study presents a novel approach for the rapid and sensitive detection of ENX in aquatic environments using molecularly imprinted polymer-based triple-ratio fluorescence (MIP-TRF) nanosensor. The nanosensor is constructed based on a photoinduced electron transfer (PET) mechanism, combining the high selectivity of molecular imprinting technology with the high sensitivity and anti-interference capability of triple-ratio fluorescence. By optimizing modifiers, eluents, and reaction conditions, the nanosensor demonstrates excellent selectivity and sensitivity, with a detection limit as low as 0.008 mg/L and good linearity over a concentration range of 0.05-7.0 mg/L. The recovery rate in river water samples was between 98.88 % and 102.76 %. To assess the potential application of the sensor, preliminary tests were also conducted by integrating the MIP-TRF nanosensor with a paper-based microfluidic chip, showing that the sensor offers higher detection speed, simplicity, and cost-effectiveness compared to traditional methods. This provides an efficient and convenient solution for the environmental monitoring of ENX and similar contaminants. |
| WOS关键词 | VISUAL DETECTION ; FLUOROQUINOLONES |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001498371500002 |
| 资助机构 | National Natural Science Foundation of China Major Scientific Research Instrument Development Project ; National Natural Science Foundation of China ; Shandong Natural Science Foundation General Project |
| 源URL | [http://ir.yic.ac.cn/handle/133337/41112]  |
| 专题 | 烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室 |
| 通讯作者 | Zhang, Xin; Li, Bowei; Chen, Lingxin |
| 作者单位 | 1.Zhejiang Univ, ZJU Hangzhou Global Sci & Technol Innovat Ctr, Hangzhou 311215, Zhejiang, Peoples R China 2.Harbin Inst Technol Weihai, China Sch Marine Sci & Technol, Weihai 264209, Shandong, Peoples R China 3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Coastal Zone Ecol Environm Monitoring Technol & Eq, CAS Key Lab Coastal Zone Environm Proc & Ecol Reme, Yantai 264003, Shandong, Peoples R China 4.Laoshan Lab, Qingdao 266237, Shandong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Chao,Wen, Yuhao,Wang, Siyu,et al. A molecularly imprinted polymer-based triple-ratio fluorescence nanosensor integrated with a paper-based microfluidic chip for rapid detection of enoxacin[J]. TALANTA,2025,295:12. |
| APA | Wang, Chao.,Wen, Yuhao.,Wang, Siyu.,Xiang, Jiawen.,Hu, Die.,...&Chen, Lingxin.(2025).A molecularly imprinted polymer-based triple-ratio fluorescence nanosensor integrated with a paper-based microfluidic chip for rapid detection of enoxacin.TALANTA,295,12. |
| MLA | Wang, Chao,et al."A molecularly imprinted polymer-based triple-ratio fluorescence nanosensor integrated with a paper-based microfluidic chip for rapid detection of enoxacin".TALANTA 295(2025):12. |
入库方式： OAI收割
来源：烟台海岸带研究所
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