Heavy Metal Ion Detection Based on Lateral Flow Assay Technology: Principles and Applications
文献类型：期刊论文
| 作者 | Xie, Xiaobo2; Hu, Xinyue2; Cao, Xin1; Zhou, Qianhui1; Yang, Wei1; Yu, Ranran1; Liu, Shuaiqi1; Hu, Huili2; Qi, Ji1; Zhang, Zhiyang1 |
| 刊名 | BIOSENSORS-BASEL
 |
| 出版日期 | 2025-07-07 |
| 卷号 | 15期号:7页码:21 |
| 关键词 | lateral flow assay heavy metal ion detection nucleic acids antigen-antibody environmental monitoring food safety |
| DOI | 10.3390/bios15070438 |
| 通讯作者 | Qi, Ji(jqi@yic.ac.cn) ; Zhang, Zhiyang(zyzhang@yic.ac.cn) |
| 英文摘要 | Heavy metal ions pose a significant threat to the environment and human health due to their high toxicity and bioaccumulation. Traditional instrumentations, although sensitive, are often complex, costly, and unsuitable for on-site rapid detection of heavy metal ions. Lateral flow assay technology has emerged as a research hotspot due to its rapid, simple, and cost-effective advantages. This review summarizes the applications of lateral flow assay technology based on nucleic acid molecules and antigen-antibody interactions in heavy metal ion detection, focusing on recognition mechanisms such as DNA probes, nucleic acid enzymes, aptamers, and antigen-antibody binding, as well as signal amplification strategies on lateral flow testing strips. By incorporating these advanced technologies, the sensitivity and specificity of lateral flow assays have been significantly improved, enabling highly sensitive detection of various heavy metal ions, including Hg2+, Cd2+, Pb2+, and Cr3+. In the future, the development of lateral flow assay technology for detection of heavy metal ions will focus on multiplex detection, optimization of signal amplification strategies, integration with portable devices, and standardization and commercialization. With continuous technological advancements, lateral flow assay technology will play an increasingly important role in environmental monitoring, food safety, and public health. |
| WOS关键词 | RAPID DETECTION ; IMMUNOCHROMATOGRAPHIC ASSAY ; COLORIMETRIC DETECTION ; GOLD NANOPARTICLES ; VISUAL DETECTION ; RP-HPLC ; MERCURY ; STRIP ; BIOSENSOR ; WATER |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Instruments & Instrumentation |
| 语种 | 英语 |
| WOS记录号 | WOS:001535378700001 |
| 资助机构 | Key Deployment Project of the Centre for Ocean Mega-Research of Science, Chinese Academy of Sciences ; National Natural Science Foundation of China ; Taishan Scholars Program ; Natural Science Foundation of Shandong Province ; Special Fund for the Scholar Program of Yantai |
| 源URL | [http://ir.yic.ac.cn/handle/133337/41283]  |
| 专题 | 烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室 |
| 通讯作者 | Qi, Ji; Zhang, Zhiyang |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 2.Harbin Inst Technol Weihai, Sch Marine Sci & Technol, Weihai 264209, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xie, Xiaobo,Hu, Xinyue,Cao, Xin,et al. Heavy Metal Ion Detection Based on Lateral Flow Assay Technology: Principles and Applications[J]. BIOSENSORS-BASEL,2025,15(7):21. |
| APA | Xie, Xiaobo.,Hu, Xinyue.,Cao, Xin.,Zhou, Qianhui.,Yang, Wei.,...&Zhang, Zhiyang.(2025).Heavy Metal Ion Detection Based on Lateral Flow Assay Technology: Principles and Applications.BIOSENSORS-BASEL,15(7),21. |
| MLA | Xie, Xiaobo,et al."Heavy Metal Ion Detection Based on Lateral Flow Assay Technology: Principles and Applications".BIOSENSORS-BASEL 15.7(2025):21. |
入库方式： OAI收割
来源：烟台海岸带研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。