Sensitive and Facile Detection of Aloin via N,F-CD-Coated Test Strips Coupled with a Miniaturized Fluorimeter
文献类型：期刊论文
| 作者 | Wei, Guo1; Wang, Chuanliang3,4; Wang, Rui1; Zhang, Peng1; Geng, Xuhui4; Li, Jinhua2; Ostovan, Abbas2; Chen, Lingxin2; Song, Zhihua1 |
| 刊名 | BIOMOLECULES
 |
| 出版日期 | 2025-07-21 |
| 卷号 | 15期号:7页码:14 |
| 关键词 | aloin nitrogen and fluorine-doped carbon dots (N,F-CDs) test strips fluorescence analysis real samples |
| DOI | 10.3390/biom15071052 |
| 通讯作者 | Song, Zhihua(zhihuasong08@yeah.net) |
| 英文摘要 | Aloin, a kind of active phenolic component, is sourced from Aloe vera. Recently, the determination of aloin has received enormous attention, owing to its positive performance (including anti-tumor, antibacterial, detoxification, liver protection, anti-stomach damage, and skin protection activities) and painful side effects (increased carcinogenicity caused by excessive use of aloin) impacting human health. This investigation was inspired by the good fluorescence properties of carbon dots (CDs); CD-based sensors have aroused a great deal of interest due to their excellent sensitivity and selectivity. Thus, it is of great significance to develop novel CD-based sensors for aloin determination. Herein, N,F-CDs were designed and synthesized through a convenient hydrothermal strategy; the synthesized N,F-CDs possessed good fluorescence performance and a small particle size (near 4.3 nm), which demonstrated the successful preparation of N,F-CDs. The resulting N,F-CDs possessed a large Stokes shift and could emit a highly stable green fluorescence. The fluorescence of the N,F-CDs could be effectively quenched by aloin through the inner filter effect. Furthermore, the synthesis procedure was easy to operate. Finally, the N,F-CD-coated test strips were fabricated and combined with a miniaturized fluorimeter for the fluorescence detection of aloin via the inner filter effect for the first time. The N,F-CD-coated test strips were fabricated and used for the fluorescence sensing of aloin, and the results were compared with a typical ultraviolet (UV) method. The N,F-CD-coated test strips exhibited high recovery (96.9 similar to 106.1%) and sensitivity (31.8 nM, n = 3), good selectivity, low sample consumption (1 mu L), high speed (5 min), good stability, and anti-interference properties. The results indicate that N,F-CD-coated test strips are applicable for the quantitative determination of aloin in bovine serum, orange juice, and urine samples. |
| WOS关键词 | CARBON DOTS ; FLUORESCENT-PROBE ; VERA |
| WOS研究方向 | Biochemistry & Molecular Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:001536713500001 |
| 资助机构 | Shandong Provincial Natural Science Foundation ; National Natural Science Foundation of China ; Youth Innovation Team Plan of Shandong Province |
| 源URL | [http://ir.yic.ac.cn/handle/133337/41289]  |
| 专题 | 烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室 |
| 通讯作者 | Song, Zhihua |
| 作者单位 | 1.Yantai Univ, Collaborat Innovat Ctr Adv Drug Univ Delivery Syst, Key Lab Mol Pharmacol & Drug Evaluat, Sch Pharm,Minist Educ, Yantai 264005, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, CAS Key Lab Separat Sci Analyt Chem, Dalian Inst Chem Phys, 457 Zhongshan Rd, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wei, Guo,Wang, Chuanliang,Wang, Rui,et al. Sensitive and Facile Detection of Aloin via N,F-CD-Coated Test Strips Coupled with a Miniaturized Fluorimeter[J]. BIOMOLECULES,2025,15(7):14. |
| APA | Wei, Guo.,Wang, Chuanliang.,Wang, Rui.,Zhang, Peng.,Geng, Xuhui.,...&Song, Zhihua.(2025).Sensitive and Facile Detection of Aloin via N,F-CD-Coated Test Strips Coupled with a Miniaturized Fluorimeter.BIOMOLECULES,15(7),14. |
| MLA | Wei, Guo,et al."Sensitive and Facile Detection of Aloin via N,F-CD-Coated Test Strips Coupled with a Miniaturized Fluorimeter".BIOMOLECULES 15.7(2025):14. |
入库方式： OAI收割
来源：烟台海岸带研究所
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