中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Surface enhanced Raman scattering (SERS) for traditional Chinese medicine analysis: Current status and future perspectives

文献类型:期刊论文

作者Zhao, Rui2; Wang, Qishuo2; Wang, Yunqing1,2; Mei, Rongchao4; Wang, Xiaoyan4; Chen, Lingxin1,3
刊名TRAC-TRENDS IN ANALYTICAL CHEMISTRY
出版日期2025-12-01
卷号193页码:22
关键词Traditional Chinese medicine Surface-enhanced Raman scattering Quality assessment Safety evaluation Active ingredient screening Pharmacokinetic analysis
ISSN号0165-9936
DOI10.1016/j.trac.2025.118479
通讯作者Wang, Yunqing(yqwang@yic.ac.cn) ; Chen, Lingxin(lxchen@yic.ac.cn)
英文摘要Traditional Chinese medicine (TCM) is a traditional treasure and its efficacy has been verified through thousands of years of practice. The standardization of TCM quality and the elucidation of pharmacological mechanisms are the requisites for its current development and application. Due to its complex multi-component nature, analysis is highly challenging. Developing advanced TCM analysis technology is a crucial task for facilitating the modernization of TCM. Surface enhanced Raman spectroscopy (SERS) technique, as a potent optical technique, possesses unique advantages including high sensitivity, high spectral resolution, simple sample pretreatment, rapid detection, and has thus achieved distinctive applications in TCM analysis. This review outlines the current situation of SERS in the analysis of active ingredients, authenticity identification, quality control, processing method monitoring, harmful substance detection and compound prescription analysis. Additionally, it presents the capabilities of SERS in the study of pharmacological action mechanisms from the perspectives of drug-target interaction, drug metabolism, and intracellular signaling pathways. Finally, the recent progress of SERS that can improve TCM analysis (such as novel SERS substrates, quantitative analysis strategies, combination with artificial intelligence (AI), etc.) is forecasted and emerging application directions like TCM plant cultivation monitoring, active ingredient screening, in vivo tracking of TCM nano-formulations, and personalized medicine for TCM therapies are also envisioned.
WOS关键词BOTANICAL DIETARY-SUPPLEMENTS ; THIN-LAYER-CHROMATOGRAPHY ; RAPID DETECTION ; PESTICIDE-RESIDUES ; SENSITIVE DETECTION ; GOLD NANOSTARS ; AG NPS ; NANOPARTICLES ; SPECTROSCOPY ; IDENTIFICATION
WOS研究方向Chemistry
语种英语
WOS记录号WOS:001591729200001
资助机构National Natural Science Foundation of China ; Taishan Scholar Project Special Funding ; Special Fund for Leading Scholar Program of Yantai
源URL[http://ir.yic.ac.cn/handle/133337/41468]  
专题烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
通讯作者Wang, Yunqing; Chen, Lingxin
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
2.Shandong Univ Tradit Chinese Med, Res Inst Marine Tradit Chinese Med, Qingdao 266112, Peoples R China
3.Shaoxing Univ, Inst Adv Study, Shaoxing 312000, Peoples R China
4.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China
推荐引用方式
GB/T 7714
Zhao, Rui,Wang, Qishuo,Wang, Yunqing,et al. Surface enhanced Raman scattering (SERS) for traditional Chinese medicine analysis: Current status and future perspectives[J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY,2025,193:22.
APA Zhao, Rui,Wang, Qishuo,Wang, Yunqing,Mei, Rongchao,Wang, Xiaoyan,&Chen, Lingxin.(2025).Surface enhanced Raman scattering (SERS) for traditional Chinese medicine analysis: Current status and future perspectives.TRAC-TRENDS IN ANALYTICAL CHEMISTRY,193,22.
MLA Zhao, Rui,et al."Surface enhanced Raman scattering (SERS) for traditional Chinese medicine analysis: Current status and future perspectives".TRAC-TRENDS IN ANALYTICAL CHEMISTRY 193(2025):22.

入库方式: OAI收割

来源:烟台海岸带研究所

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