Lathyrane and jatrophane diterpenoids: Potential lipid-lowering agents from Euphorbia helioscopia L
文献类型：期刊论文
| 作者 | Chen, Sheng; Zhao, Wen-Zheng; Zhang, Zhi-Yan; Yue, Hui-Lan; Shi, Qiang-Qiang |
| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2025 |
| 卷号 | 186 |
| 关键词 | E. helioscopia Diterpenoids Lipid-lowering |
| 英文摘要 | Four new Euphorbia diterpenoids, helioranes A-C (1-3) and heliophane A (4), and six know analogues were isolated from the whole plants of Euphorbia helioscopia. Among them, compounds 1-3 are typical lathyranes varying with substituents, compound 4 is a rare 7,8-seco-jatrophane diterpenoid. The structures of the novel compounds were unequivocally established through an integrated approach combining spectroscopic analyses and quantum chemical calculations. Lipid-lowering activity screening in 3 T3-L1 cells demonstrated that compound 3 and 9 exhibited potential inhibitory effects on lipid accumulation. |
| 源URL | [http://210.75.249.4/handle/363003/62386]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Chen, Sheng,Zhao, Wen-Zheng,Zhang, Zhi-Yan,et al. Lathyrane and jatrophane diterpenoids: Potential lipid-lowering agents from Euphorbia helioscopia L[J]. FITOTERAPIA,2025,186. |
| APA | Chen, Sheng,Zhao, Wen-Zheng,Zhang, Zhi-Yan,Yue, Hui-Lan,&Shi, Qiang-Qiang.(2025).Lathyrane and jatrophane diterpenoids: Potential lipid-lowering agents from Euphorbia helioscopia L.FITOTERAPIA,186. |
| MLA | Chen, Sheng,et al."Lathyrane and jatrophane diterpenoids: Potential lipid-lowering agents from Euphorbia helioscopia L".FITOTERAPIA 186(2025). |
入库方式： OAI收割
来源：西北高原生物研究所
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