Integrated Stacked Design Nanobullet for High Photothermal Conversion in Dual-Mode Lateral Flow Immunoassay
文献类型：期刊论文
| 作者 | Jia, Huilin; Wang, Biao; Wang, Meilin; Shu, Rui; Liu, Sijie; Li, Yuechun; Sun, Jing; Wang, Jianlong |
| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2025 |
| 卷号 | 97期号:11页码:6268 |
| 英文摘要 | Salmonella enterica serovar typhimurium (S. typhimurium), a prevalent foodborne bacterium, necessitates creating sensitive and rapid detection methods for food safety, with lateral flow immunoassays (LFIAs) using nanomaterials as signal tracers being particularly effective. Enhancements in performance and sensitivity are not restricted to the material alone, we propose an integrated stacked concept, which combines amorphous active sites, hollow morphology for enhanced reflection, and symmetric structure for strong absorption resonance. This approach leads to significant photothermal enhancement (eta = 60.66%) and is supported by finite element analysis (|E|max 2 = 3100). A hollow nanobullet (RuTe2) was created, featuring a vivid colorimetric signal enhancing the detection range, a large specific surface area (approximate to 6:1) for improved antibody binding, and excellent photothermal properties facilitating dual-mode transduction. After 5 min of binding, the detection limits of RuTe2-LFIA for S. typhimurium after 12 min were 2398.83 cfu mL-1 (colorimetric) and 977.23 cfu mL-1 (photothermal), which were 36.14 and 88.72 times lower than the values of AuNPs-LFIA (86696.19 cfu mL-1). The superior performance of RuTe2-LFIA suggests potential advancements in photothermal materials for point-of-care testing. |
| 源URL | [http://210.75.249.4/handle/363003/62502]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Jia, Huilin,Wang, Biao,Wang, Meilin,et al. Integrated Stacked Design Nanobullet for High Photothermal Conversion in Dual-Mode Lateral Flow Immunoassay[J]. ANALYTICAL CHEMISTRY,2025,97(11):6268. |
| APA | Jia, Huilin.,Wang, Biao.,Wang, Meilin.,Shu, Rui.,Liu, Sijie.,...&Wang, Jianlong.(2025).Integrated Stacked Design Nanobullet for High Photothermal Conversion in Dual-Mode Lateral Flow Immunoassay.ANALYTICAL CHEMISTRY,97(11),6268. |
| MLA | Jia, Huilin,et al."Integrated Stacked Design Nanobullet for High Photothermal Conversion in Dual-Mode Lateral Flow Immunoassay".ANALYTICAL CHEMISTRY 97.11(2025):6268. |
入库方式： OAI收割
来源：西北高原生物研究所
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