Empirical correction decomposition method (ECDM): enhancing accuracy of quantitative measurement in spectral CT
文献类型：期刊论文
| 作者 | Wang, Chengmin1,3; Wang, Zhe3,4; Li, Mohan3,4; Liu, Yuedong1,3; Zhang, Xiaomei2; Wei, Cunfeng1,3,4; Wei, Long1,3,4 |
| 刊名 | PHYSICS IN MEDICINE AND BIOLOGY
 |
| 出版日期 | 2025-01-05 |
| 卷号 | 70期号:1页码:16 |
| 关键词 | material decomposition spectral CT quantitative imaging |
| ISSN号 | 0031-9155 |
| DOI | 10.1088/1361-6560/ad9a4a |
| 通讯作者 | Wang, Zhe(wangzhe@ihep.ac.cn) ; Wei, Cunfeng(weicf@ihep.ac.cn) |
| 英文摘要 | Objective. Spectral CT and material decomposition methods are crucial for precise material identification and quantitative composition analysis in preclinical research and clinical diagnosis. The empirical material decomposition method is widely used for its straightforward modeling approach, independence from spectral and detector response knowledge, and operational convenience. However, this method has limited decomposition accuracy and its precision depends on the choice of calibration phantoms. Approach. To address these issues, we propose an empirical correction decomposition method (ECDM). The innovation of this method lies in its ability to conveniently estimate and correct empirical decomposition errors using a specially designed calibration phantom. First, the specially designed calibration phantom for ECDM undergoes empirical decomposition initially to establish the relationship between decomposition errors and decomposition values. Then, ECDM estimates and corrects the error of empirical decomposition values. Main results. In the phantom experiments, ECDM improves the decomposition accuracy of empirical methods, effectively reducing the different decomposition errors caused by four different sizes of calibration phantoms from a maximum of 144% to within 25%. In the mouse experiments, ECDM achieves accurate quantification of contrast agents in biological tissues, outperforming the other two methods. The absolute error percentages of ECDM in the decomposition results of the two standard iodine solutions are both less than 5%. Significance. ECDM significantly improves decomposition accuracy and reduces the impact of the size of the empirical calibration phantom. Overall, our method based on spectral CT is very convenient and practical for the quantitative measurement in biomedical applications. |
| WOS关键词 | IMAGE-RECONSTRUCTION ; ENERGY ; HEMORRHAGE ; ESTIMATOR ; CONTRAST |
| WOS研究方向 | Engineering ; Radiology, Nuclear Medicine & Medical Imaging |
| 语种 | 英语 |
| WOS记录号 | WOS:001391201200001 |
| 出版者 | IOP Publishing Ltd |
| 源URL | [http://119.78.100.205/handle/311034/24169]  |
| 专题 | 中国科学院古脊椎动物与古人类研究所 |
| 通讯作者 | Wang, Zhe; Wei, Cunfeng |
| 作者单位 | 1.Univ Chinese Acad Sci, Sch Nucl Sci & Technol, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Inst Vertebrate Paleontol & Paleoanthropol, Beijing 100044, Peoples R China 3.Chinese Acad Sci, Inst High Energy Phys, Beijing Engn Res Ctr Radiog Tech & Equipment, Beijing 100049, Peoples R China 4.Jinan Lab Appl Nucl Sci, Jinan 250131, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Chengmin,Wang, Zhe,Li, Mohan,et al. Empirical correction decomposition method (ECDM): enhancing accuracy of quantitative measurement in spectral CT[J]. PHYSICS IN MEDICINE AND BIOLOGY,2025,70(1):16. |
| APA | Wang, Chengmin.,Wang, Zhe.,Li, Mohan.,Liu, Yuedong.,Zhang, Xiaomei.,...&Wei, Long.(2025).Empirical correction decomposition method (ECDM): enhancing accuracy of quantitative measurement in spectral CT.PHYSICS IN MEDICINE AND BIOLOGY,70(1),16. |
| MLA | Wang, Chengmin,et al."Empirical correction decomposition method (ECDM): enhancing accuracy of quantitative measurement in spectral CT".PHYSICS IN MEDICINE AND BIOLOGY 70.1(2025):16. |
入库方式： OAI收割
来源：古脊椎动物与古人类研究所
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