Bronze Age cheese reveals human-Lactobacillus interactions over evolutionary history
文献类型：期刊论文
| 作者 | Liu, Yichen2,3; Miao, Bo2; Li, Wenying4; Hu, Xingjun5; Bai, Fan2,3; Abuduresule, Yidilisi4; Liu, Yalin2,3; Zheng, Zequan2,3; Wang, Wenjun2,6; Chen, Zehui2,3 |
| 刊名 | CELL
 |
| 出版日期 | 2024-10-17 |
| 卷号 | 187期号:21页码:5891-+ |
| ISSN号 | 0092-8674 |
| DOI | 10.1016/j.cell.2024.08.008 |
| 英文摘要 | Despite the long history of consumption of fermented dairy, little is known about how the fermented microbes were utilized and evolved over human history. Here, by retrieving ancient DNA of Bronze Age kefir cheese (similar to 3,500 years ago) from the Xiaohe cemetery, we explored past human-microbial interactions. Although it was previously suggested that kefir was spread from the Northern Caucasus to Europe and other regions, we found an additional spreading route of kefir from Xinjiang to inland East Asia. Over evolutionary history, the East Asian strains gained multiple gene clusters with defensive roles against environmental stressors, which can be a result of the adaptation of Lactobacillus strains to various environmental niches and human selection. Overall, our results highlight the role of past human activities in shaping the evolution of human-related microbes, and such insights can, in turn, provide a better understanding of past human behaviors. |
| WOS关键词 | ANCIENT ; PRODUCTS ; BACTERIA ; FOODS ; KEFIR ; CAVE ; MILK ; TOOL |
| 资助项目 | National Natural Science Foundation of China[41925009] ; Fundamental Research Funds for the Central Universities ; Chinese Academy of Sciences (CAS)[YSBR-019] ; National Natural Science Foundation of China[42302021] ; Chinese Academy of Sciences (CAS)[2023000065] ; Feng Foundation of Biomedical Research |
| WOS研究方向 | Biochemistry & Molecular Biology ; Cell Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:001389449400001 |
| 出版者 | CELL PRESS |
| 源URL | [http://119.78.100.205/handle/311034/24251]  |
| 专题 | 中国科学院古脊椎动物与古人类研究所 |
| 通讯作者 | Yang, Yimin; Fu, Qiaomei |
| 作者单位 | 1.Univ Chinese Acad Sci, Dept Archaeol & Anthropol, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Inst Vertebrate Paleontol & Paleoanthropol, Key Lab Vertebrate Evolut & Human Origins, Beijing 100035, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Xinjiang Cultural Rel & Archaeol Inst, Urumqi 830000, Peoples R China 5.Xinjiang Univ, Sch Hist, Res Ctr Governance Chinas Northwest Frontier Hist, Udumqi 830046, Peoples R China 6.Natl Ctr Archaeol, Sci & Technol Archaeol, Beijing 100013, Peoples R China 7.Peking Univ Third Hosp, Dept Obstet & Gynecol, Ctr Reprod Med, Beijing 100191, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Yichen,Miao, Bo,Li, Wenying,et al. Bronze Age cheese reveals human-Lactobacillus interactions over evolutionary history[J]. CELL,2024,187(21):5891-+. |
| APA | Liu, Yichen.,Miao, Bo.,Li, Wenying.,Hu, Xingjun.,Bai, Fan.,...&Fu, Qiaomei.(2024).Bronze Age cheese reveals human-Lactobacillus interactions over evolutionary history.CELL,187(21),5891-+. |
| MLA | Liu, Yichen,et al."Bronze Age cheese reveals human-Lactobacillus interactions over evolutionary history".CELL 187.21(2024):5891-+. |
入库方式： OAI收割
来源：古脊椎动物与古人类研究所
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