Convergent functional evolution of mRNA-binding proteins fuels allotetraploid adaptation in cyprinids
文献类型：期刊论文
| 作者 | Liu, Fujiang2; Wu, Jiahong1; Dong, Yichen2; Song, Yue3,5; Tong, Baichuan2; Peng, Yicheng2; He, Liyan2; Xu, Luohao1; Fan, Guangyi3; Wu, Feixiang4 |
| 刊名 | CELL REPORTS
 |
| 出版日期 | 2025-12-23 |
| 卷号 | 44期号:12页码:25 |
| ISSN号 | 2639-1856 |
| DOI | 10.1016/j.celrep.2025.116635 |
| 英文摘要 | Polyploidy, the duplication of the entire genome, is a major force in vertebrate evolution, yet how new polyploid species survive and prosper remains unclear. Here, we present a chromosome-level genome of the cyprinid Spinibarbus caldwelli, whose allotetraploid event is dated to similar to 4 million years ago based on transposable element distributions in its two subgenomes. Genomic analyses reveal unique patterns of homoeologous exchanges between the two subgenomes, indicating a gradual evolutionary process prior to their suppression. Furthermore, we identify a striking pattern of accelerated evolution of RNA-binding proteins across independently evolved tetraploid cyprinids. Functional assays of one such protein, Tia1, demonstrate that the tetraploid orthologs may be more efficient at stress granule disassembly than those of diploid relatives. These findings suggest that improved cellular stress management, particularly in RNA processing, might be a key adaptation that has enabled the evolutionary success of polyploid cyprinids. |
| WOS关键词 | GENOME PROVIDES INSIGHTS ; PHYLOGENETIC ANALYSIS ; ALIGNMENT ; TRANSCRIPTOME ; RECOMBINATION ; SEQUENCE ; PARALLEL ; TOOL ; CONSEQUENCES ; MECHANISMS |
| 资助项目 | National Natural Science Foundation of China[42272013] ; Natural Science Foundation of Xiamen[3502Z202473009] ; Xiamen University |
| WOS研究方向 | Cell Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:001630346300006 |
| 出版者 | CELL PRESS |
| 源URL | [http://119.78.100.205/handle/311034/25118]  |
| 专题 | 中国科学院古脊椎动物与古人类研究所 |
| 通讯作者 | Fan, Guangyi; Wu, Feixiang; Wang, Bo; Qu, Qingming |
| 作者单位 | 1.Southwest Univ, Integrat Sci Ctr Germplasm Creat Western China Cho, Key Lab Freshwater Fish Reprod & Dev, Minist Educ,Sch Life Sci, Chongqing 400715, Peoples R China 2.Xiamen Univ, Fac Med & Life Sci, Sch Life Sci, State Key Lab Cellular Stress Biol, Xiamen 361102, Peoples R China 3.BGI Res, Qingdao 266555, Peoples R China 4.Chinese Acad Sci, Key Lab Vertebrate Evolut & Human Origins, Inst Vertebrate Paleontol & Paleoanthropol, Beijing 100044, Peoples R China 5.Univ Copenhagen, Dept Biol, Lab Integrat Biomed, Univ Pk 13, DK-2100 Copenhagen, Denmark |
| 推荐引用方式 GB/T 7714 | Liu, Fujiang,Wu, Jiahong,Dong, Yichen,et al. Convergent functional evolution of mRNA-binding proteins fuels allotetraploid adaptation in cyprinids[J]. CELL REPORTS,2025,44(12):25. |
| APA | Liu, Fujiang.,Wu, Jiahong.,Dong, Yichen.,Song, Yue.,Tong, Baichuan.,...&Qu, Qingming.(2025).Convergent functional evolution of mRNA-binding proteins fuels allotetraploid adaptation in cyprinids.CELL REPORTS,44(12),25. |
| MLA | Liu, Fujiang,et al."Convergent functional evolution of mRNA-binding proteins fuels allotetraploid adaptation in cyprinids".CELL REPORTS 44.12(2025):25. |
入库方式： OAI收割
来源：古脊椎动物与古人类研究所
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