The effect of non-pharmaceutical interventions on influenza throughout the COVID-19 pandemic: an 8-year interrupted time series study
文献类型：期刊论文
| 作者 | Li, Zhirui3; Zhou, Lijun3; Zhou, Xingyu3; Zhang, Qian2; Fan, Zixuan1; Xiao, Chongkun3,4 |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2026-01-29 |
| 卷号 | 16期号:1页码:6593 |
| 关键词 | Influenza Covid-19 Interrupted time series analysis (ITSA) Immunity debt Non-pharmacological interventions |
| ISSN号 | 2045-2322 |
| DOI | 10.1038/s41598-026-37911-2 |
| 产权排序 | 3 |
| 文献子类 | Article |
| 英文摘要 | Limited information is available on the impact of non-pharmaceutical interventions (NPIs) and immune debt on influenza during COVID-19. This retrospective population-based research examined the effect of the COVID-19 pandemic on the prevalence of influenza-like illness (ILI) cases and influenza positive cases in Sichuan Province. Interrupted time series analysis (ITS) was conducted using data gathered from surveillance hospitals throughout 21 cities, including information on patients diagnosed with ILI and positive nucleic acid testing. Subsequent to the implementation of NPIs, there was a notable temporary reduction in both the incidence of ILI cases and confirmed influenza cases, decreasing by 94.7% and 98.0%, respectively (P<0.001). The weekly trend in influenza-positive cases was notable (+4.1%/week, P=0.001). Following the execution of the second-phase intervention, the fluctuations in the transient changes of ILI patients and influenza-positive cases varied; nonetheless, both subsequently exhibited a significant declining trend (P<0.001). Temperature had a substantial negative correlation with both indicators (P<0.001), resulting in a reduction of instances by 13.0% and 11.5%, respectively; humidity demonstrated no statistically significant impact on either. Our data demonstrate that NPIs significantly reduce two influenza outcome indicators in the short term; nevertheless, they do not effectuate a sustainable alteration in the long-term increasing trend of influenza. Through the examination of the dynamic effects of NPIs on influenza transmission, we provide policymakers with an enhanced evaluative instrument, a decision-making framework, and theoretical backing, while also contemplating the prospective advantages and hazards of NPIs for additional respiratory infectious diseases in the future. |
| URL标识 | 查看原文 |
| WOS研究方向 | Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:001694159800010 |
| 出版者 | NATURE PORTFOLIO |
| 源URL | [http://ir.igsnrr.ac.cn/handle/311030/221246]  |
| 专题 | 区域可持续发展分析与模拟院重点实验室_外文论文 |
| 通讯作者 | Xiao, Chongkun |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Reg Sustainable Dev Modeling, Inst Geog Sci & Nat Resources Res, Beijing 100101, Peoples R China; 2.Xiamen Fifth Hosp, Dept Oncol, Xiamen 361000, Fujian, Peoples R China; 3.Sichuan Prov Ctr Dis Control & Prevent, Dept Dis Control & Prevent, Chengdu 610000, Sichuan, Peoples R China; 4.6 Zhongxue Rd, Chengdu 610000, Sichuan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Zhirui,Zhou, Lijun,Zhou, Xingyu,et al. The effect of non-pharmaceutical interventions on influenza throughout the COVID-19 pandemic: an 8-year interrupted time series study[J]. SCIENTIFIC REPORTS,2026,16(1):6593. |
| APA | Li, Zhirui,Zhou, Lijun,Zhou, Xingyu,Zhang, Qian,Fan, Zixuan,&Xiao, Chongkun.(2026).The effect of non-pharmaceutical interventions on influenza throughout the COVID-19 pandemic: an 8-year interrupted time series study.SCIENTIFIC REPORTS,16(1),6593. |
| MLA | Li, Zhirui,et al."The effect of non-pharmaceutical interventions on influenza throughout the COVID-19 pandemic: an 8-year interrupted time series study".SCIENTIFIC REPORTS 16.1(2026):6593. |
入库方式： OAI收割
来源：地理科学与资源研究所
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