Warming-induced drought is altering forest structure and function, leading to significant declines in tree growth. However, it remains unclear which forests are most vulnerable to these stressors. Using long-term and large-scale tree-ring width and climate datasets from 1901 to 2015, we assessed drought-induced growth loss (GL), growth variability (CV), resistance (Rt) and recovery (Rc) across diverse climate regions. The results indicated that GL, CV, and Rc were significantly higher in arid regions compared to humid regions, while the opposite was true for Rt. GL, CV, and Rc exhibit a latitudinal gradient, increasing from high latitudes (80 degrees N) to low latitudes (10 degrees N), while they are decreasing along the aridity index (AI) gradient. Notably, GL is most pronounced in tropical and dryland, where significant growth declines showed in over 90 % of sites. Additionally, angiosperms show significantly higher GL, CV, and Rc than gymnosperms. These results highlight the need for targeted management strategies that consider the unique climatic and ecological conditions of each region to effectively mitigate tree growth loss in a warming climate.