Lake-terminating glaciers retreat and thin faster than land-terminating glaciers, yet their long-term dynamics remain underexplored. Using multi source-remote sensing data combined with glacier velocity and elevation change datasets, we investigated their distribution and evolution in the Himalaya and Southeastern Tibet from 1990 to 2020. By 2020, 577 lake-terminating glaciers (2561.5 +/- 11.8 km(2)) had been identified, representing similar to 2% of all glaciers by number and similar to 10% by area. Of these, 246 glaciers maintained contact with proglacial lakes (Type 1 change), while 331 developed new lakes (Type 2 change). Additionally, 173 glaciers detached from lakes (Type 3 change). Variations in glacier-lake contact strongly modulate glacier dynamics. Type 1 change glaciers experienced the largest area loss (73.8 +/- 13.1 km(2)), whereas Type 2 change glaciers showed the greatest average retreat distance (1.06 +/- 0.05 km). Among Type 1 change glaciers (>5 km(2)) with significant velocity trends, 22% accelerated and 78% decelerated, while all Type 3 change glaciers with significant velocity trends consistently decelerated. These findings underscore the pivotal influence of proglacial lake evolution on glacier dynamics, advancing our understanding of glacier-lake interactions on the Tibetan Plateau and beyond.