Transcriptome Analysis Reveals the Molecular Mechanism Involved in Carotenoid Absorption and Metabolism in the Ridgetail White Prawn Exopalaemon carinicauda
文献类型：期刊论文
| 作者 | Han, Yumin1,2; Yu, Yang1,2,3; Zhang, Chengsong1,2,3; Li, Shihao1,2,3; Yuan, Jianbo1,2,3; Li, Fuhua1,2,3 |
| 刊名 | ANIMALS
 |
| 出版日期 | 2025-05-01 |
| 卷号 | 15期号:9页码:18 |
| 关键词 | astaxanthin supplementation
|
| ISSN号 | 2076-2615 |
| DOI | 10.3390/ani15091314 |
| 通讯作者 | Yu, Yang(yuyang@qdio.ac.cn) ; Li, Fuhua(fhli@qdio.ac.cn) |
| 英文摘要 | Astaxanthin plays a vital role in pigmentation, immune function, reproduction, and antioxidation in aquatic species. To clarify the molecular mechanism of astaxanthin utilization in Exopalaemon carinicauda (E. carinicauda), we conducted a comparative transcriptome analysis on the intestine, hepatopancreas, and muscle of E. carinicauda, fed with an astaxanthin diet and a normal diet. A total of 144 differentially expressed genes (DEGs) were identified in three tissues between the two groups. Genes related to absorption and transport, such as LDLR and the vitellogenin receptor, were upregulated in the intestine after astaxanthin supplementation, while the ileal sodium/bile acid cotransporter-like gene was downregulated. In the hepatopancreas, genes involved in lipid storage and degradation were significantly altered at the transcriptional level, including Kruppel 1-like, ACSBG2, delta(7)-sterol 5(6)-desaturase-like, and PNLIPRP2. In the muscle, the expression of the FABP gene was significantly upregulated, while several actin and troponin genes were significantly downregulated. Furthermore, GSEA analysis on the transcriptomes of three tissues revealed that astaxanthin supplementation influenced the expression of genes related to antioxidation and growth, indicating that astaxanthin may have a positive impact on the growth, development, and resistance of organisms. The data from this research provide valuable insights into elucidating the molecular mechanisms underlying astaxanthin absorption and metabolism and also offer guidance for the application of astaxanthin in the aquaculture of economically important crustaceans. |
| WOS关键词 | KRUPPEL-LIKE ; ASTAXANTHIN ; TRANSPORTERS ; EXPRESSION ; INSIGHTS ; LIPASE ; SALMON |
| 资助项目 | National Key R&D Program of China ; Key Research and Development Program of Shandong[2021LZGC029] ; Taishan Scholars Program ; [2022YFD2400203] |
| WOS研究方向 | Agriculture ; Veterinary Sciences ; Zoology |
| 语种 | 英语 |
| WOS记录号 | WOS:001486082600001 |
| 出版者 | MDPI |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/202037]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Yu, Yang; Li, Fuhua |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, State Key Lab Breeding Biotechnol & Sustainable Aq, Qingdao 266000, Peoples R China 2.Univ Chinese Acad Sci, Coll Earth Sci, Beijing 100049, Peoples R China 3.Qingdao Marine Sci & Technol Ctr, Lab Marine Biol & Biotechnol, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Han, Yumin,Yu, Yang,Zhang, Chengsong,et al. Transcriptome Analysis Reveals the Molecular Mechanism Involved in Carotenoid Absorption and Metabolism in the Ridgetail White Prawn Exopalaemon carinicauda[J]. ANIMALS,2025,15(9):18. |
| APA | Han, Yumin,Yu, Yang,Zhang, Chengsong,Li, Shihao,Yuan, Jianbo,&Li, Fuhua.(2025).Transcriptome Analysis Reveals the Molecular Mechanism Involved in Carotenoid Absorption and Metabolism in the Ridgetail White Prawn Exopalaemon carinicauda.ANIMALS,15(9),18. |
| MLA | Han, Yumin,et al."Transcriptome Analysis Reveals the Molecular Mechanism Involved in Carotenoid Absorption and Metabolism in the Ridgetail White Prawn Exopalaemon carinicauda".ANIMALS 15.9(2025):18. |
入库方式： OAI收割
来源：海洋研究所
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