LncRNA-Mediated Tissue-Specific Plastic Responses to Salinity Changes in Oysters
文献类型：期刊论文
| 作者 | Zhang, Mengshi1; Zhao, Jinlong1; Li, Ao3,4,5,6,7,8; Zhao, Mingjie8; Huo, Meitong8; Deng, Jinhe8; Wang, Luping3,4; Wang, Wei2,3,4,8; Zhang, Guofan3,5,6,7; Li, Li2,3,4,5,7,8 |
| 刊名 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
 |
| 出版日期 | 2025-05-09 |
| 卷号 | 26期号:10页码:18 |
| 关键词 | estuary RNA-seq gene expression regulation stress response shellfish |
| ISSN号 | 1661-6596 |
| DOI | 10.3390/ijms26104523 |
| 通讯作者 | Li, Ao(ali@qdio.ac.cn) ; Li, Li(lili@qdio.ac.cn) |
| 英文摘要 | Salinity is a key environmental factor influencing the survival of aquatic organisms, and transcriptional plasticity is a crucial emergency response to environmental changes. However, most transcriptomic studies on salinity responses have not explored the expression patterns and regulatory mechanisms across different tissues. The Suminoe oyster (Crassostrea ariakensis), a sessile estuarine species that inhabits fluctuating salinity environments, provides an excellent model for studying the molecular basis of salinity response divergence. All eight tissues responded to acute salinity stresses and exhibited distinct tissue-specific expression patterns in both mRNA and long non-coding RNA (lncRNA) profiles across three salinity conditions. The hepatopancreas and striated muscle were identified as tissues specifically sensitive to hyper- and hypo-saline stress, respectively, based on the number, expression pattern, and plasticity of differentially expressed genes (DEGs). We established lncRNA-mRNA regulatory relationships that environmentally responsive lncRNAs enhanced DEGs' expression and underpinning tissue-specific responses. Under moderate stress, the hepatopancreas and striated muscle initiated positive responses related to water transport and shell closure, respectively. Under severe stress, the hepatopancreas activated cellular resistance pathways, while the striated muscle experienced significant cell death. Our findings provide insights into lncRNA-mediated, tissue-specific environmental responses and lay the foundation for further research into the adaptive evolution of tissue-specific regulation. |
| WOS关键词 | LOCAL ADAPTATION ; NONCODING RNAS ; CLIMATE-CHANGE ; GROWTH-RATE ; EVOLUTION ; LIMITS ; COSTS ; IDENTIFICATION ; MECHANISMS ; TOLERANCE |
| 资助项目 | Key Research and Development Program of Guangxi ; Southern Marine Science and Engineering Guangdong Laboratory (Zhanjiang)[ZJW-2024-15] ; National Natural Science Foundation of China[32471687] ; Key Research and Development Program of Shandong Province, China[ZFJH202309] ; Key Research and Development Program of Shandong Province, China[2022LZGC015] ; Youth Innovation Promotion Association, Chinese Academy of Sciences[2023215] ; National Key R&D Program of China[2022YFD2400304] ; Taishan Scholars Program[tsqn202312267] ; China Agriculture Research System of MOF[CARS-49] ; [GNK AB241484027] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001496359100001 |
| 出版者 | MDPI |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/202118]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Li, Ao; Li, Li |
| 作者单位 | 1.Qingdao Agr Univ, Coll Life Sci, Sch Marine Sci & Engn, Qingdao 266109, Peoples R China 2.Qingdao Marine Sci & Technol Ctr, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266071, Peoples R China 3.Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 5.Oyster Ind Technol Inst Zhanjiang, Southern Marine Sci & Engn Guangdong Lab Zhanjiang, Zhanjiang 524000, Peoples R China 6.Qingdao Marine Sci & Technol Ctr, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China 7.Chinese Acad Sci, Inst Oceanol, State Key Lab Breeding Biotechnol & Sustainable Aq, Qingdao 266000, Peoples R China 8.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Mengshi,Zhao, Jinlong,Li, Ao,et al. LncRNA-Mediated Tissue-Specific Plastic Responses to Salinity Changes in Oysters[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2025,26(10):18. |
| APA | Zhang, Mengshi.,Zhao, Jinlong.,Li, Ao.,Zhao, Mingjie.,Huo, Meitong.,...&Li, Li.(2025).LncRNA-Mediated Tissue-Specific Plastic Responses to Salinity Changes in Oysters.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,26(10),18. |
| MLA | Zhang, Mengshi,et al."LncRNA-Mediated Tissue-Specific Plastic Responses to Salinity Changes in Oysters".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 26.10(2025):18. |
入库方式： OAI收割
来源：海洋研究所
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