Effects of estradiol exposure on lipid metabolism in male and female sea cucumber Apostichopus japonicus
文献类型：期刊论文
| 作者 | Zhang, Shuangyan3,4,5,6,7; Zhang, Libin4,5,6,7; Goncalves, David1; Xu, Jialei2 |
| 刊名 | AQUACULTURE REPORTS
 |
| 出版日期 | 2025-09-15 |
| 卷号 | 43页码:10 |
| 关键词 | Sea cucumber Sex difference Physiology Lipid metabolism Estradiol |
| ISSN号 | 2352-5134 |
| DOI | 10.1016/j.aqrep.2025.102881 |
| 通讯作者 | Zhang, Libin(zhanglibin@qdio.ac.cn) |
| 英文摘要 | Lipids are important energy storage nutrients and signalling molecules for reproduction. Steroid hormones, including estradiol (E2), have been shown to play a key regulatory role in lipid metabolism in vertebrates. However, not much is known on the action of sex steroids in lipid metabolism in invertebrates. This study investigated the impact of exogenous E2 administration in lipid metabolism of male and female sea cucumber Apostichopus japonicus. Control females had higher crude lipid content in the body wall, but not in the intestines, as compared to control males. E2 administration significantly reduced the total lipid content in the intestine and body wall of females, but not males. The analysis of intestinal metabolites and gene expression of A. japonicus showed that E2 significantly affected the expression of genes and the levels of metabolites related with lipid metabolism pathway. The metabolism of sex hormones, triglycerides and fatty acids in females was more active as compared to males. The fatty acid degradation and glycerophospholipid metabolism pathways were disturbed by E2 administration in males. E2 significantly inhibited the activity of catalase (CAT) in the coelomic fluid, and it is speculated that E2 may have disrupted lipid metabolism by inducing oxidative imbalance in males by targeting the glycerophospholipid metabolism pathway. The study confirms that sex steroids play a significant role in regulating physiological functions in echinoderms and, in particular, that E2 might modulate lipid metabolism, as described for vertebrates. The results also suggest that exogenous administration of sex steroids could be used as a tool to regulate reproductive function to improve the rearing of A. japonicus. |
| WOS关键词 | BISPHENOL-A ; 17-BETA-ESTRADIOL ; GROWTH ; CATFISH |
| 资助项目 | Sino-Portugal Joint Laboratory in Marine and Environmental Sciences |
| WOS研究方向 | Fisheries |
| 语种 | 英语 |
| WOS记录号 | WOS:001495300500001 |
| 出版者 | ELSEVIER |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/202139]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Zhang, Libin |
| 作者单位 | 1.Univ St Joseph, Inst Sci & Environm, Macau 999078, Peoples R China 2.Zhongke Tonghe Shandong Ocean Technol Co Ltd, Dongying 257200, Peoples R China 3.Zibo Vocat Inst, Zibo 255300, Peoples R China 4.Qingdao Marine Sci & Technol Ctr, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China 5.Chinese Acad Sci, Inst Oceanol, Key Lab Breeding Biotechnol & Sustainable Aquacult, Qingdao 266071, Peoples R China 6.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 7.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Shuangyan,Zhang, Libin,Goncalves, David,et al. Effects of estradiol exposure on lipid metabolism in male and female sea cucumber Apostichopus japonicus[J]. AQUACULTURE REPORTS,2025,43:10. |
| APA | Zhang, Shuangyan,Zhang, Libin,Goncalves, David,&Xu, Jialei.(2025).Effects of estradiol exposure on lipid metabolism in male and female sea cucumber Apostichopus japonicus.AQUACULTURE REPORTS,43,10. |
| MLA | Zhang, Shuangyan,et al."Effects of estradiol exposure on lipid metabolism in male and female sea cucumber Apostichopus japonicus".AQUACULTURE REPORTS 43(2025):10. |
入库方式： OAI收割
来源：海洋研究所
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