Complete genome sequence of Lysinibacillus sp. WB86, a potential antimicrobial lanthipeptides producer
文献类型：期刊论文
| 作者 | Sun, Huai-Ying3,4; Xin, Ji-Xiang3,4; Li, Gen3,4; Zhou, Zhen-Yi3,4; Li, Xin1; Wang, Hong3,4; Yin, Qun-Jian2; Wei, Bin3,4 |
| 刊名 | MARINE GENOMICS
 |
| 出版日期 | 2025-08-15 |
| 卷号 | 82页码:4 |
| 关键词 | Complete genome Lysinibacillus Cold seep South China Sea Biosynthetic gene cluster Lanthipeptides |
| ISSN号 | 1874-7787 |
| DOI | 10.1016/j.margen.2025.101204 |
| 通讯作者 | Yin, Qun-Jian() ; Wei, Bin(binwei@zjut.edu.cn) |
| 英文摘要 | Lysinibacillus sp. WB86 was isolated from a cold seep in the South China Sea, and its complete genome was sequenced using Oxford Nanopore Technologies (ONT). The genome consists of a single circular chromosome spanning 4,537,071 bp, with a G + C content of 37 %. FastANI analysis revealed a 99.38 % average nucleotide identity (ANI) with Lysinibacillus sphaericus A1, confirming its classification as a strain of L. sphaericus. Genome annotation identified 4397 protein-coding genes, along with 111 tRNAs and 34 rRNAs. Functional categorization using the COG database assigned 84.6 % of the protein-coding genes to specific roles, with the majority involved in transcription, amino acid transport and metabolism, translation and ribosomal biogenesis, and replication, recombination, and repair. Additionally, antiSMASH-based analysis uncovered eight biosynthetic gene clusters (BGCs), only one of which exhibited high similarity (>50 %) to known BGCs. This cluster was predicted to encode novel antimicrobial lanthipeptides, suggesting potential biotechnological applications. |
| WOS关键词 | SEA-FLOOR ; METHANE |
| 资助项目 | Guangxi Key Laboratory of Beibu Gulf Marine Resources, Environment and Sustainable Development[MRESD-2024-A04] ; National Natural Science Programs of China[W2412100] ; National Natural Science Programs of China[42276137] ; National Key Research and Development Programs[2022YFC2804700] ; National Key Research and Development Programs[2022YFC2804104] |
| WOS研究方向 | Genetics & Heredity ; Marine & Freshwater Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:001548206200001 |
| 出版者 | ELSEVIER |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/203122]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Yin, Qun-Jian; Wei, Bin |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, CAS & Shandong Prov Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China 2.Minist Nat Resources, Inst Oceanog 4, Beihai 536015, Peoples R China 3.Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310014, Peoples R China 4.Zhejiang Univ Technol, Collaborat Innovat Ctr Yangtze River Delta Reg Gre, Hangzhou 310014, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Huai-Ying,Xin, Ji-Xiang,Li, Gen,et al. Complete genome sequence of Lysinibacillus sp. WB86, a potential antimicrobial lanthipeptides producer[J]. MARINE GENOMICS,2025,82:4. |
| APA | Sun, Huai-Ying.,Xin, Ji-Xiang.,Li, Gen.,Zhou, Zhen-Yi.,Li, Xin.,...&Wei, Bin.(2025).Complete genome sequence of Lysinibacillus sp. WB86, a potential antimicrobial lanthipeptides producer.MARINE GENOMICS,82,4. |
| MLA | Sun, Huai-Ying,et al."Complete genome sequence of Lysinibacillus sp. WB86, a potential antimicrobial lanthipeptides producer".MARINE GENOMICS 82(2025):4. |
入库方式： OAI收割
来源：海洋研究所
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