Genetic Resources for Research on the Regulatory Mechanism of ω-3 Fatty Acids in Oysters
文献类型：期刊论文
| 作者 | Li, Qingyuan4,5,6; Cong, Rihao1,2,3,6; Wang, Chaogang4,5,6; Wang, Wei2,5,6; Zhang, Guofan2,3,6,7,8; Qi, Haigang2,6,7; Li, Li2,4,5,6,7,8 |
| 刊名 | SCIENTIFIC DATA
 |
| 出版日期 | 2025-09-29 |
| 卷号 | 12期号:1页码:8 |
| DOI | 10.1038/s41597-025-05822-y |
| 通讯作者 | Qi, Haigang(qihaigang@qdio.ac.cn) ; Li, Li(lili@qdio.ac.cn) |
| 英文摘要 | This data descriptor presents a multi-omics resource for Crassostrea gigas and Crassostrea angulata, comprising genomic variants and transcriptomic profiles relevant to fatty acid metabolism traits. A 458-individual F2 hybrid population genotyped with a 100 K SNP array identified 344 SNPs and 742 candidate genes linked to C18:3 omega 3, EPA, and DHA variation. KEGG analysis highlighted 24 key genes, with 23 validated via GS-assisted GWAS, dominant genotype screening, and wild population resequencing. Differential expression analysis revealed 458 DEGs (266 between high/low EPA + DHA groups; 192 between species), overlapping with 152 genes from GWAS and selective sweeps. This integrated dataset provides foundational genetic references for studying omega-3 fatty acid dynamics, enabling future investigations into sustainable marine resource utilization and climate resilience. |
| WOS关键词 | GENOME-WIDE ASSOCIATION ; MODEL APPROACH ; SELECTION ; SNPS |
| 资助项目 | National Natural Science Foundation of China (National Science Foundation of China)[2022YFD2400301] ; National Key R&D Program of China[XDA 24030105] ; Strategic Priority Research Program of the Chinese Academy of Sciences[ZFJH202309] ; Key Research and Development Program of Shandong[22-3-3-hygg-2-hy] ; Key Technology Research and Industrialization Demonstration Projects of Qingdao[CARS-49] ; China Agriculture Research System of MOF[GZB20250723] ; Postdoctoral Fellowship Program (Grade B) of China Postdoctoral Science Foundation[2025M770875] ; China Postdoctoral Science Foundation ; Chinese Academy of Sciences |
| WOS研究方向 | Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:001585013900014 |
| 出版者 | NATURE PORTFOLIO |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/203560]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Qi, Haigang; Li, Li |
| 作者单位 | 1.Chinese Acad Sci, Innovat Seed Design, Wuhan 430072, Peoples R China 2.Chinese Acad Sci, Natl & Local Joint Engn Lab Ecol Mariculture, Inst Oceanol, Qingdao 266071, Peoples R China 3.Laoshan Lab, Lab Marine Biol & Biotechnol, Qingdao 266100, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 5.Laoshan Lab, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266100, Peoples R China 6.Chinese Acad Sci, Inst Oceanol, Ctr Ocean Mega Sci, CAS & Shandong Prov Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 7.Shandong Technol Innovat Ctr Oyster Seed Ind, Qingdao 266105, Peoples R China 8.Inst Hydrobiol, Key Lab Breeding Biotechnol & Sustainable Aquacult, Wuhan 430072, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Qingyuan,Cong, Rihao,Wang, Chaogang,et al. Genetic Resources for Research on the Regulatory Mechanism of ω-3 Fatty Acids in Oysters[J]. SCIENTIFIC DATA,2025,12(1):8. |
| APA | Li, Qingyuan.,Cong, Rihao.,Wang, Chaogang.,Wang, Wei.,Zhang, Guofan.,...&Li, Li.(2025).Genetic Resources for Research on the Regulatory Mechanism of ω-3 Fatty Acids in Oysters.SCIENTIFIC DATA,12(1),8. |
| MLA | Li, Qingyuan,et al."Genetic Resources for Research on the Regulatory Mechanism of ω-3 Fatty Acids in Oysters".SCIENTIFIC DATA 12.1(2025):8. |
入库方式： OAI收割
来源：海洋研究所
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