Extensive Recombination Suppression and Genetic Degeneration of a Young ZW Sex Chromosome System in Halfbeak Fish
文献类型：期刊论文
| 作者 | Xing, Teng-Fei1,4; Li, Yu-Long1,4; Yang, Hao1,3,4; Charlesworth, Deborah2; Liu, Jin-Xian1,4 |
| 刊名 | MOLECULAR BIOLOGY AND EVOLUTION
 |
| 出版日期 | 2025-07-01 |
| 卷号 | 42期号:7页码:20 |
| 关键词 | sex chromosomes halfbeaks recombination suppression evolution genome |
| ISSN号 | 0737-4038 |
| DOI | 10.1093/molbev/msaf151 |
| 通讯作者 | Charlesworth, Deborah(Deborah.Charlesworth@ed.ac.uk) ; Liu, Jin-Xian(jinxianliu@gmail.com) |
| 英文摘要 | Sex chromosome systems have evolved independently across the tree of life, at different times in the past, and the evolutionary consequences of lacking recombination in sex-linked regions have been characterized in many old-established systems. However, empirical studies of young sex chromosomes are still scarce, especially in vertebrates. Integrating whole-genome sequencing data of two species of halfbeak fish, Hyporhamphus sajori and Hyporhamphus intermedius, we identified the sex-determining system in H. sajori as female heterogamety, involving a large fully sex-linked ZW region (similar to 26 Mb) on chromosome 5. The closest relative, H. intermedius, has a small sex-linked region on a different chromosome and shows male heterogamety, suggesting at least one turnover in this fish genus. The H. sajori sex-linked region includes two evolutionary strata, but the estimated Z-W divergence times are small, less than 3 million years for the older stratum, which is less than between the two species. Nevertheless, this evolutionarily young W-linked region is enriched with repetitive sequences, differs from the ancestral state by five inversions, and about one-third of its protein-coding genes have already become nonfunctional. Transcriptomic analysis suggests that some form of dosage compensation may already be evolving for some sex-linked genes. |
| WOS关键词 | Y-CHROMOSOMES ; EVOLUTION ; GENOME ; MODEL ; RECONSTRUCTION ; ADAPTATION ; SEQUENCE ; INSIGHTS ; REGION ; VISUALIZATION |
| 资助项目 | National Natural Science Foundation of China[32370563] ; National Natural Science Foundation of China[42176133] ; Shandong Provincial Natural Science Foundation[ZR2023QD121] ; Shandong Provincial Natural Science Foundation[ZR2024QD028] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Evolutionary Biology ; Genetics & Heredity |
| 语种 | 英语 |
| WOS记录号 | WOS:001527959800001 |
| 出版者 | OXFORD UNIV PRESS |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/202556]  |
| 专题 | 海洋研究所_海洋生态与环境科学重点实验室 |
| 通讯作者 | Charlesworth, Deborah; Liu, Jin-Xian |
| 作者单位 | 1.Qingdao Marine Sci & Technol Ctr, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China 2.Univ Edinburgh, Inst Ecol & Evolut, Sch Biol Sci, Edinburgh EH9 3FL, Scotland 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xing, Teng-Fei,Li, Yu-Long,Yang, Hao,et al. Extensive Recombination Suppression and Genetic Degeneration of a Young ZW Sex Chromosome System in Halfbeak Fish[J]. MOLECULAR BIOLOGY AND EVOLUTION,2025,42(7):20. |
| APA | Xing, Teng-Fei,Li, Yu-Long,Yang, Hao,Charlesworth, Deborah,&Liu, Jin-Xian.(2025).Extensive Recombination Suppression and Genetic Degeneration of a Young ZW Sex Chromosome System in Halfbeak Fish.MOLECULAR BIOLOGY AND EVOLUTION,42(7),20. |
| MLA | Xing, Teng-Fei,et al."Extensive Recombination Suppression and Genetic Degeneration of a Young ZW Sex Chromosome System in Halfbeak Fish".MOLECULAR BIOLOGY AND EVOLUTION 42.7(2025):20. |
入库方式： OAI收割
来源：海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。