Genome-wide Parallelism Underlies Rapid Freshwater Adaptation Fueled by Standing Genetic Variation in a Wild Fish
文献类型：期刊论文
| 作者 | Yang, Hao1,2,3; Li, Yu-Long1,2; Xing, Teng-Fei1,2; Wu, Jian-Hui4,5; Wang, Ting4; Zhu, Ming-Sheng6; Liu, Jin-Xian1,2 |
| 刊名 | MOLECULAR BIOLOGY AND EVOLUTION
 |
| 出版日期 | 2025-07-01 |
| 卷号 | 42期号:7页码:14 |
| 关键词 | parallel evolution rapid adaptation complex traits polygenic adaptation standing genetic variation allele frequency changes |
| ISSN号 | 0737-4038 |
| DOI | 10.1093/molbev/msaf160 |
| 通讯作者 | Liu, Jin-Xian(jinxianliu@gmail.com) |
| 英文摘要 | A fundamental focus of ecological and evolutionary biology is determining how natural populations adapt to environmental changes. Rapid parallel phenotypic evolution can be leveraged to uncover the genetics of adaptation. Using population genomic approaches, we investigated the genetic architecture underlying rapid parallel freshwater adaptation of Neosalanx brevirostris by comparing four freshwater-resident populations with their common ancestral anadromous population. We demonstrated that the rapid parallel adaptation to freshwater followed a complex polygenic architecture and was characterized by genomic-level parallelism, which proceeded predominantly through repeated selection on the preexisting standing genetic variations. Frequencies of the genome-wide adaptive standing variations were moderate in the ancestral anadromous population, which had pre-adapted to fluctuating salinities. Relatively large allele frequency shifts were observed at some adaptive single-nucleotide polymorphisms (SNPs) during parallel adaptation to freshwater environments, with a large fraction of freshwater-favored alleles being fixed or nearly fixed. These adaptive SNPs were involved in multiple biological functions associated with osmoregulation, immunoregulation, locomotion, metabolism, etc., which were highly consistent with the polygenic architecture of adaptive divergence between the two ecotypes involving multiple complex physiological and behavioral traits. This work provides insight into the mechanisms by which natural populations rapidly evolve to changes in the environment and highlights the importance of standing genetic variation for the evolutionary potential of populations facing global environmental changes. |
| WOS关键词 | POPULATION-GENETICS ; EVOLUTION ; OSMOREGULATION ; DIVERGENCE ; EXPRESSION ; STRESS ; FORMAT |
| 资助项目 | National Natural Science Foundation of China[42176133] ; National Natural Science Foundation of China[32370563] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Evolutionary Biology ; Genetics & Heredity |
| 语种 | 英语 |
| WOS记录号 | WOS:001533444800001 |
| 出版者 | OXFORD UNIV PRESS |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/202598]  |
| 专题 | 海洋研究所_海洋生态与环境科学重点实验室 |
| 通讯作者 | Liu, Jin-Xian |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 2.Qingdao Marine Sci & Technol Ctr, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Shanghai Aquat Wildlife Conservat & Res Ctr, Shanghai 200092, Peoples R China 5.Shanghai Monitoring Stn Aquat Biol Resources Yangt, Shanghai 202162, Peoples R China 6.Off Taihu Fishery Management Comm, Suzhou 215104, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Hao,Li, Yu-Long,Xing, Teng-Fei,et al. Genome-wide Parallelism Underlies Rapid Freshwater Adaptation Fueled by Standing Genetic Variation in a Wild Fish[J]. MOLECULAR BIOLOGY AND EVOLUTION,2025,42(7):14. |
| APA | Yang, Hao.,Li, Yu-Long.,Xing, Teng-Fei.,Wu, Jian-Hui.,Wang, Ting.,...&Liu, Jin-Xian.(2025).Genome-wide Parallelism Underlies Rapid Freshwater Adaptation Fueled by Standing Genetic Variation in a Wild Fish.MOLECULAR BIOLOGY AND EVOLUTION,42(7),14. |
| MLA | Yang, Hao,et al."Genome-wide Parallelism Underlies Rapid Freshwater Adaptation Fueled by Standing Genetic Variation in a Wild Fish".MOLECULAR BIOLOGY AND EVOLUTION 42.7(2025):14. |
入库方式： OAI收割
来源：海洋研究所
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