Deciphering the photodegradation fate of Brevetoxins: Kinetics, degradation pathways, and toxicity evaluation
文献类型：期刊论文
| 作者 | Chi, Lianbao1,2; Zhang, Xiaona2,4; Yuan, Yongquan1,2,4; Shen, Huihui3; Yu, Zhiming1,2,4; Song, Xiuxian1,2,4 |
| 刊名 | HARMFUL ALGAE
 |
| 出版日期 | 2025-11-01 |
| 卷号 | 149页码:11 |
| 关键词 | Harmful algal blooms Karenia brevis Brevetoxins Photodegradation Transformation products |
| ISSN号 | 1568-9883 |
| DOI | 10.1016/j.hal.2025.102944 |
| 通讯作者 | Song, Xiuxian(songxx@qdio.ac.cn) |
| 英文摘要 | Karenia brevis blooms have emerged as an increasing global concern due to their capacity to produce brevetoxins (BTXs), which are potent marine neurotoxins. The ecological impact of BTXs is significantly modulated by the natural attenuation process, with photodegradation playing a pivotal role. Nevertheless, the fate of BTXs following photodegradation remains inadequately understood. This study elucidates the photodegradation kinetics of three representative BTXs and identifies their transformation products (TPs). The observed first-order photodegradation rate coefficient, based on the logarithmic transformation of dissolved BTXs concentrations against irradiation time, ranged from 0.84 to 2.49 h(-1). Utilizing high-resolution liquid chromatography-mass spectrometry, three, four, and five TPs were identified for BTX-1, BTX-2, and BTX-3, respectively. All TPs underwent substantial structural modifications with significant mass reductions. Proposed primary photodegradation pathways encompass Ring-opening, alkyl chain cleavage, hydrolysis, dehydroxylation, epoxidation, and beta-elimination. Additionally, in silico prediction indicated that the biodegradability of TPs was significantly higher than that of the parent toxins. However, certain TPs exhibited greater toxicities compared to their parent toxins. The coexistence of multiple BTXs and TPs may lead to synergistic toxicity, thereby posing secondary risks to aquatic organisms. Overall, this research will enhance a comprehensive understanding of the environmental behaviors and risks associated with BTXs. |
| WOS关键词 | HARMFUL ALGAL BLOOMS ; FLORIDA RED TIDE ; KARENIA-BREVIS ; PHOTOCHEMICAL TRANSFORMATION ; MARINE AEROSOL ; HUMAN EXPOSURE ; TOXIN ; PRODUCTS ; PBTX-2 ; DESTRUCTION |
| 资助项目 | Intergovernmental Innovation Cooperation Project of the Ministry of Science and Technology[2022YFE0136400] ; National Natural Science Foundation of China[42376210] ; National Natural Science Foundation of China[42276220] |
| WOS研究方向 | Marine & Freshwater Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:001565858000001 |
| 出版者 | ELSEVIER |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/203290]  |
| 专题 | 海洋研究所_海洋生态与环境科学重点实验室 |
| 通讯作者 | Song, Xiuxian |
| 作者单位 | 1.Qingdao Marine Sci & Technol Ctr, Lab Marine Ecol & Environm Sci, Qingdao 266200, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 3.Qingdao Tech Coll, Qingdao 266555, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chi, Lianbao,Zhang, Xiaona,Yuan, Yongquan,et al. Deciphering the photodegradation fate of Brevetoxins: Kinetics, degradation pathways, and toxicity evaluation[J]. HARMFUL ALGAE,2025,149:11. |
| APA | Chi, Lianbao,Zhang, Xiaona,Yuan, Yongquan,Shen, Huihui,Yu, Zhiming,&Song, Xiuxian.(2025).Deciphering the photodegradation fate of Brevetoxins: Kinetics, degradation pathways, and toxicity evaluation.HARMFUL ALGAE,149,11. |
| MLA | Chi, Lianbao,et al."Deciphering the photodegradation fate of Brevetoxins: Kinetics, degradation pathways, and toxicity evaluation".HARMFUL ALGAE 149(2025):11. |
入库方式： OAI收割
来源：海洋研究所
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