Development of a seaweed-derived polymeric nanocomposite with anti-infective properties against wound pathogens
文献类型：期刊论文
| 作者 | Dinakaran, Vengateshwaran Thasu2; Santhaseelan, Henciya2; Devendiran, Velmurugan2; Krishnan, Muthukumar3; Jizhou, Duan3; Selvamony, Armstrong-Altrin John1; Rathinam, Arthur James2 |
| 刊名 | POLYMER BULLETIN
 |
| 出版日期 | 2025-05-26 |
| 页码 | 34 |
| 关键词 | Seaweed GsAu/CeO2/TiO(2)NPs Metal oxide nanocomposites Anti-infective Biocompatible |
| ISSN号 | 0170-0839 |
| DOI | 10.1007/s00289-025-05790-8 |
| 通讯作者 | Santhaseelan, Henciya(henzmarine@gmail.com) ; Rathinam, Arthur James(james@bdu.ac.in) |
| 英文摘要 | Gracilaria salicornia was used to synthesize nanoparticles from its aqueous extract, and Padina gymnospora was a source of sodium alginate (SA)-based hydrogel. The synthesized nanoparticles with sodium alginate, a nanocomposite (NC) thin film, termed GsAu/CeO2/TiO2NC, was successfully fabricated. The integration of SA with NC was investigated and confirmed using SEM, EDX, FT-IR, XRD, and TGA analyses. Thermostability of GsAu/CeO2/TiO2NC thin film was validated through thermogravimetric analysis (TGA) and viscosity of the fabricated NC was systematically assessed. The NC exhibited MICs of 6.25, 12.5 and 25 mu g/mL against E. coli, Staphylococcus aureus and Candida albicans. The NC thin film exhibited potent anti-infective properties, achieving biofilm inhibition efficiencies of 76.47 +/- 0.98% for E. coli, 71.25 +/- 0.40% for S. aureus, and 66.17 +/- 0.53% for C. albicans. Also, it demonstrated mature biofilm eradication rates of 68.79 +/- 0.52%, 60.64 +/- 0.14%, and 57.62 +/- 0.84%, respectively. The polydisperse produced GsAu/CeO2/TiO2NC thin film formed with different metallic NP concentrations, resulting in a fluctuating structure. The incorporation of metallic nanoparticles enhanced the pore size of SA polysaccharides in the nanocomposite, facilitating the successful structural formation. The NC demonstrated antioxidant activity at 0.8 mg/mL, free radical scavenging at 70.64 +/- 0.92%, and non-hemolytic potential at 0.5 mg/mL. These results imply that the produced NC is suitable for elevated antimicrobial applications in anti-infective wound dressing. [GRAPHICS] . |
| WOS关键词 | CERIUM OXIDE NANOPARTICLES ; ANTIBACTERIAL ACTIVITY ; GOLD NANOPARTICLES ; SODIUM ALGINATE ; FILMS ; GREEN ; COMPOSITES ; DELIVERY ; ACID |
| 资助项目 | National Centre for Coastal Research (NCCR) ; DST-FIST[SR/FST/ES-I/2019/62 (C)] ; DST-WTI[DST/TMD/EWO/WTI/2K19/EWFH/2019/81] ; DST-PURSE (USIC)[MoES/PAMC/DOM/53/2023] ; DST-PURSE (USIC)[E-12929] ; DST-PURSE (USIC)[2024 VEC004] ; Chinese Academy of Sciences (CAS), President's International Fellowship Initiative (PIFI), Institute of Oceanology, People's Republic of China |
| WOS研究方向 | Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:001495247800001 |
| 出版者 | SPRINGER |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/202112]  |
| 专题 | 海洋研究所_海洋腐蚀与防护研究发展中心 |
| 通讯作者 | Santhaseelan, Henciya; Rathinam, Arthur James |
| 作者单位 | 1.Univ Nacl Autonoma Mexico, Unidad Proc Ocean & Costeros, Inst Ciencias Mar & Limnol, Ciudad Univ, Mexico City 04510, Mexico 2.Bharathidasan Univ, Dept Marine Sci, Tiruchirappalli 620024, Tamil Nadu, India 3.Chinese Acad Sci, Inst Oceanol, Key Lab Adv Marine Mat, Key Lab Marine Environm Corros & Biofouling, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Dinakaran, Vengateshwaran Thasu,Santhaseelan, Henciya,Devendiran, Velmurugan,et al. Development of a seaweed-derived polymeric nanocomposite with anti-infective properties against wound pathogens[J]. POLYMER BULLETIN,2025:34. |
| APA | Dinakaran, Vengateshwaran Thasu.,Santhaseelan, Henciya.,Devendiran, Velmurugan.,Krishnan, Muthukumar.,Jizhou, Duan.,...&Rathinam, Arthur James.(2025).Development of a seaweed-derived polymeric nanocomposite with anti-infective properties against wound pathogens.POLYMER BULLETIN,34. |
| MLA | Dinakaran, Vengateshwaran Thasu,et al."Development of a seaweed-derived polymeric nanocomposite with anti-infective properties against wound pathogens".POLYMER BULLETIN (2025):34. |
入库方式： OAI收割
来源：海洋研究所
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