Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope
文献类型：期刊论文
| 作者 | Lian, Wu1,2; Wu, Mingyi1; Huang, Ning3,4; Gao, Na1; Xiao, Chuang1,2 ; Li, Zi1; Zhang, Zhigang1; Zheng, Yongtang3,4; Peng, Wenlie2; Zhao, Jinhua1
|
| 刊名 | BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
 |
| 出版日期 | 2013-10-01 |
| 卷号 | 1830期号:10页码:4681-4691 |
| 关键词 | Glycosaminoglycan Anti-human immunodeficiency virus activity Envelope glycoprotein 120 Cluster of Differentiation 4 induced epitope Biolayer interferometry Structure-activity relationship |
| ISSN号 | 0304-4165 |
| 通讯作者 | Zheng, YT (reprint author), Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Yunnan, Peoples R China.,zhengyt@mail.kiz.ac.cn ; pengwenlie@21cn.com ; zhaojinhua@yahoo.com |
| 英文摘要 | Background: Fucosylated glycosaminoglycan (FG) is a novel glycosaminoglycan with a chondroitin sulfate-like backbone and fucose sulfate branches. The aim of this study is to investigate the mechanism and structure-activity relationships (SAR) of FG for combating HIV-1 infection. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 学科主题 | Biochemistry & Molecular Biology ; Biophysics |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 关键词[WOS] | IMMUNODEFICIENCY-VIRUS TYPE-1 ; FREE-RADICAL DEPOLYMERIZATION ; CUCUMBER THELENATA-ANANAS ; CORECEPTOR BINDING-SITE ; ANTI-HIV ACTIVITY ; CHONDROITIN SULFATE ; SEA-CUCUMBER ; ENVELOPE GLYCOPROTEIN ; ANTIRETROVIRAL THERAPY ; DEXTRAN SULFATE |
| 收录类别 | SCI |
| 资助信息 | Yunnan Provincial Science and Technology Department in China [2010CI116, 2012BC011, 2012FB177]; National Natural Science Foundation of China [81102372]; Outstanding Technical Talent Foundation of the Chinese Academy of Sciences; West Light Foundation of the Chinese Academy of Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000323854900031 |
| 公开日期 | 2013-11-12 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/17281]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Sun Yat Sen Univ, Sch Life Sci, Guangzhou 510275, Guangdong, Peoples R China 3.Chinese Acad Sci, Key Lab Anim Models & Human Dis Mech, Kunming 650223, Yunnan, Peoples R China 4.Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lian, Wu,Wu, Mingyi,Huang, Ning,et al. Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope[J]. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,2013,1830(10):4681-4691. |
| APA | Lian, Wu.,Wu, Mingyi.,Huang, Ning.,Gao, Na.,Xiao, Chuang.,...&Zhao, Jinhua.(2013).Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,1830(10),4681-4691. |
| MLA | Lian, Wu,et al."Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope".BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1830.10(2013):4681-4691. |
入库方式： OAI收割
来源：昆明植物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。