Diterpenoid compounds from Vitex agnus-castus
文献类型：期刊论文
| 作者 | Pal, Mahesh1,2; Li, Sheng-Hong2 ; Tewari, Shri Krishan1; Sun, Han-Dong2
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| 刊名 | CHEMISTRY OF NATURAL COMPOUNDS
 |
| 出版日期 | 2013-09-01 |
| 卷号 | 49期号:4页码:635-638 |
| 关键词 | diterpenoid Vitex agnus-castus Verbenaceae vitexlactam cytotoxicity |
| ISSN号 | 0009-3130 |
| 通讯作者 | Pal, M (reprint author), Natl Bot Res Inst, CSIR, Phytochem Div, Lucknow 226001, Uttar Pradesh, India.,drmpal.nbri@rediffmail.com |
| 英文摘要 | A new diterpenoid alkaloid having an alpha,beta-unsaturated gamma-lactam moiety, 9 alpha-hydroxy-13(14)-labden-16,15-amide (1), together with five known ones, was isolated from the fruits of Vitex angus-castus. The structure of 1 was elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques.The cytotoxicity of each compound was evaluated against human chronic myelogenous leukemia (K562) cell lines. Compound 1 was found to be the most potent with IC50 value of 0.70 mu g/mL. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences |
| 学科主题 | Chemistry, Medicinal ; Chemistry, Organic |
| 类目[WOS] | Chemistry, Medicinal ; Chemistry, Organic |
| 研究领域[WOS] | Pharmacology & Pharmacy ; Chemistry |
| 关键词[WOS] | FRUIT |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000324830200012 |
| 公开日期 | 2013-11-12 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/17284]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Natl Bot Res Inst, CSIR, Phytochem Div, Lucknow 226001, Uttar Pradesh, India 2.Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Pal, Mahesh,Li, Sheng-Hong,Tewari, Shri Krishan,et al. Diterpenoid compounds from Vitex agnus-castus[J]. CHEMISTRY OF NATURAL COMPOUNDS,2013,49(4):635-638. |
| APA | Pal, Mahesh,Li, Sheng-Hong,Tewari, Shri Krishan,&Sun, Han-Dong.(2013).Diterpenoid compounds from Vitex agnus-castus.CHEMISTRY OF NATURAL COMPOUNDS,49(4),635-638. |
| MLA | Pal, Mahesh,et al."Diterpenoid compounds from Vitex agnus-castus".CHEMISTRY OF NATURAL COMPOUNDS 49.4(2013):635-638. |
入库方式： OAI收割
来源：昆明植物研究所
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