Preparation and biomedical applications of artificial cells
文献类型：期刊论文
| 作者 | Xu, Qian1,2; Zhang, Zeping2,3; Lui, Pauline Po Yee4; Lu, Liang2,3; Li, Xiaowu1; Zhang, Xing2,3 |
| 刊名 | MATERIALS TODAY BIO
 |
| 出版日期 | 2023-12-01 |
| 卷号 | 23页码:14 |
| 关键词 | Artificial cells Bottom-up approach Microcapsules Cellular communication Bioreactors |
| ISSN号 | 2590-0064 |
| DOI | 10.1016/j.mtbio.2023.100877 |
| 通讯作者 | Li, Xiaowu(xwli@mail.neu.edu.cn) ; Zhang, Xing(xingzhang@imr.ac.cn) |
| 英文摘要 | Artificial cells have received much attention in recent years as cell mimics with typical biological functions that can be adapted for therapeutic and diagnostic applications, as well as having an unlimited supply. Although remarkable progress has been made to construct complex multifunctional artificial cells, there are still significant differences between artificial cells and natural cells. It is therefore important to understand the techniques and challenges for the fabrication of artificial cells and their applications for further technological advancement. The key concepts of top-down and bottom-up methods for preparing artificial cells are summarized, and the advantages and disadvantages of the bottom-up methods are compared and critically discussed in this review. Potential applications of artificial cells as drug carriers (microcapsules), as signaling regulators for coordinating cellular communication and as bioreactors for biomolecule fabrication, are further discussed. The challenges and future trends for the development of artificial cells simulating the real activities of natural cells are finally described. |
| 资助项目 | National Natural Science Foundation of China[52273278] ; Liao Ning Revitalization Talents Program[XLYC2007112] |
| WOS研究方向 | Engineering ; Materials Science |
| 语种 | 英语 |
| WOS记录号 | WOS:001128798900001 |
| 出版者 | ELSEVIER |
| 资助机构 | National Natural Science Foundation of China ; Liao Ning Revitalization Talents Program |
| 源URL |  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 通讯作者 | Li, Xiaowu; Zhang, Xing |
| 作者单位 | 1.Northeastern Univ, Key Lab Anisotropy & Texture Mat, Dept Mat Phys & Chem, Sch Mat Sci & Engn,Minist Educ, Shenyang 110819, Liaoning, Peoples R China 2.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China 3.Univ Sci & Technol China, Dept Mat Sci & Engn, Hefei 230026, Anhui, Peoples R China 4.Chinese Univ Hong Kong, Dept Orthopaed & Traumatol, Hong Kong 999077, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Qian,Zhang, Zeping,Lui, Pauline Po Yee,et al. Preparation and biomedical applications of artificial cells[J]. MATERIALS TODAY BIO,2023,23:14. |
| APA | Xu, Qian,Zhang, Zeping,Lui, Pauline Po Yee,Lu, Liang,Li, Xiaowu,&Zhang, Xing.(2023).Preparation and biomedical applications of artificial cells.MATERIALS TODAY BIO,23,14. |
| MLA | Xu, Qian,et al."Preparation and biomedical applications of artificial cells".MATERIALS TODAY BIO 23(2023):14. |
入库方式： OAI收割
来源：金属研究所
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