Enhanced sensing of bacteria biomarkers by ZnO and graphene oxide decorated PEDOT film
文献类型：期刊论文
| 作者 | Malachy Udowo, Victor1,2; Unimuke, Tomsmith O.3; Louis, Hitler3,4; Udoh, Inime Ime5; Edet, Henry O.3; Okafor, Peter C.3 |
| 刊名 | JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
 |
| 出版日期 | 2024-03-09 |
| 页码 | 14 |
| 关键词 | Sensors N-acyl homoserine lactone quorum sensing PEDOT graphene oxide |
| ISSN号 | 0739-1102 |
| DOI | 10.1080/07391102.2024.2328740 |
| 通讯作者 | Malachy Udowo, Victor(victorudowo@mail.ustc.edu.cn) ; Louis, Hitler(Louis.hitler@unical.edu.ng) |
| 英文摘要 | Developing a biofilm biomarker detector and inhibitor will immensely benefit efforts geared at curbing infectious diseases and microbiologically induced corrosion of medical implants, marine vessels and buried steel pipelines. N-Acyl homoserine lactones (AHLs) are important biomarkers gram-negative bacteria use for communication. In this work, we investigated the interactions between three AHL molecules and graphene oxide (GO) and ZnO nanomaterials embedded in conjugated poly(3,4-ethylenedioxythiophene) (PEDOT) film. The results show that PEDOT/GO/ZnO detected AHLs to a considerable extent with adsorption enthalpies of -4.02, -4.87 and -4.97 KJ/mol, respectively, for N-(2-oxotetrahydrofuran-3-yl)heptanamide (AHL1), 2-hydroxy-N-(2-oxotetrahydrofuran-3-yl)nonanamide (AHL2) and (E)-3-(3-hydroxyphenyl)-N-(2-oxotetrahydrofuran-3-yl)acrylamide (AHL3) molecules. The ZnO nanoparticles facilitated charge redistribution and transfer, thereby enhancing the conductivity and overall sensitivity of the substrate toward the AHLs. The adsorption distance and sites of interactions further tuned the charge migration and signal generation by the substrate, thus affirming the suitability of the modeled thin film as a sensor material. Excellent stability and conductivity were maintained before and after the adsorption of each AHL molecule. Moreover, the desorption time for each AHL molecule was calculated, and the result affirmed that the modeled film materials are promising for developing highly sensitive biosensors.Communicated by Ramaswamy H. Sarma |
| WOS研究方向 | Biochemistry & Molecular Biology ; Biophysics |
| 语种 | 英语 |
| WOS记录号 | WOS:001187419300001 |
| 出版者 | TAYLOR & FRANCIS INC |
| 源URL |  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 通讯作者 | Malachy Udowo, Victor; Louis, Hitler |
| 作者单位 | 1.Chinese Acad Sci, Inst Met Res, Shenyang, Peoples R China 2.Univ Sci & Technol China, Sch Mat Sci & Engn, Hefei, Peoples R China 3.Univ Calabar, Dept Pure & Appl Chem, Calabar, Nigeria 4.Chettinad Acad Res & Educ, Chettinad Hosp & Res Inst, Fac Allied Hlth Sci, Kelambakkam, Tamil Nadu, India 5.Tech Univ Denmark, Dept Chem & Biochem Engn, Kongens Lyngby, Denmark |
| 推荐引用方式 GB/T 7714 | Malachy Udowo, Victor,Unimuke, Tomsmith O.,Louis, Hitler,et al. Enhanced sensing of bacteria biomarkers by ZnO and graphene oxide decorated PEDOT film[J]. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS,2024:14. |
| APA | Malachy Udowo, Victor,Unimuke, Tomsmith O.,Louis, Hitler,Udoh, Inime Ime,Edet, Henry O.,&Okafor, Peter C..(2024).Enhanced sensing of bacteria biomarkers by ZnO and graphene oxide decorated PEDOT film.JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS,14. |
| MLA | Malachy Udowo, Victor,et al."Enhanced sensing of bacteria biomarkers by ZnO and graphene oxide decorated PEDOT film".JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2024):14. |
入库方式： OAI收割
来源：金属研究所
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