Degradable magnesium alloy suture promotes fibrocartilaginous interface regeneration in a rat rotator cuff transosseous repair model
文献类型：期刊论文
| 作者 | Zhang, Baoxiang1,4; Zhang, Wen2,3; Zhang, Fei1,4; Ning, Chao1,5; An, Mingyang1,4; Yang, Ke2; Tan, Lili2; Zhang, Qiang1 |
| 刊名 | JOURNAL OF MAGNESIUM AND ALLOYS
 |
| 出版日期 | 2024 |
| 卷号 | 12期号:1页码:384-393 |
| 关键词 | Rotator cuff repair Mg alloy wire Tendon -bone healing Fibrocartilaginous interface. |
| ISSN号 | 2213-9567 |
| DOI | 10.1016/j.jma.2022.05.009 |
| 通讯作者 | Tan, Lili(lltan@imr.ac.cn) ; Zhang, Qiang(301zq@live.cn) |
| 英文摘要 | Despite transosseous rotator cuff tear repair using sutures is widely accepted for tendon-bone fixation, the fibrocartilaginous enthesis regeneration is still hardly achieved with the traditional sutures. In the present work, degradable magnesium (Mg) alloy wire was applied to suture supraspinatus tendon in a rat acute rotator cuff tear model with Vicryl Plus 4-0 absorbable suture as control. The shoulder joint humerus-supraspinatus tendon complex specimens were retrieved at 4, 8, and 12 weeks after operation. The Mg alloy suture groups showed better biomechanical properties in terms of ultimate load to failure. Gross observation showed that hyperplastic response of the scar tissue at the tendon-bone interface is progressively alleviated over time in the both Mg alloy suture and Vicryl suture groups. In the histological analysis, for Mg alloy suture groups, chondrocytes appear to proliferate at 4 weeks postoperatively, and the tendon-bone interface showed an orderly structural transition zone at 8 weeks postoperatively. The collagenous fiber tended to be aligned and the tendon-bone interlocking structures apparently formed, where transitional structure from unmineralized fibrocartilage to mineralized fibrocartilage was closer to the native fibrocartilaginous enthesis. In vivo degradation of the magnesium alloy wire was completed within 12 weeks. The results indicated that Mg alloy wire was promising as degradable suture with the potential to promotes fibrocartilaginous interface regeneration in rotator cuff repair. (c) 2022 Chongqing University. Publishing services provided by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ ) Peer review under responsibility of Chongqing University |
| 资助项目 | National Key Research and Development Program of China[2020YFC1107501] ; National Natural Science Foundation of China[51971222] ; National Natural Science Foundation of China[51801220] ; Natural Science Foundation of Liaoning Province of China[2020 -MS -001] ; DongGuan Innovative Research Team Program[2020607134012] ; Military Translational Medicine Fund of Chinese PLA General Hospital[ZH19008] ; Capital's Funds for Health Improvement and Research[CFH 2022-2-5051] ; DongGuan Science and Technology Service Network Initiative[20201600200042] |
| WOS研究方向 | Metallurgy & Metallurgical Engineering |
| 语种 | 英语 |
| WOS记录号 | WOS:001189060500001 |
| 出版者 | KEAI PUBLISHING LTD |
| 资助机构 | National Key Research and Development Program of China ; National Natural Science Foundation of China ; Natural Science Foundation of Liaoning Province of China ; DongGuan Innovative Research Team Program ; Military Translational Medicine Fund of Chinese PLA General Hospital ; Capital's Funds for Health Improvement and Research ; DongGuan Science and Technology Service Network Initiative |
| 源URL |  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 通讯作者 | Tan, Lili; Zhang, Qiang |
| 作者单位 | 1.Chinese Peoples Liberat Army Gen Hosp, Dept Sports Med, Beijing 100853, Peoples R China 2.Chinese Acad Sci, Shi Changxu Innovat Ctr Adv Mat, Inst Met Res, Shenyang 110016, Peoples R China 3.Univ Sci & Technol China, Sch Mat Sci & Engn, Shenyang 110016, Peoples R China 4.Med Sch PLA, Beijing 100853, Peoples R China 5.Chinese Peoples Liberat Army Gen Hosp, Inst Orthoped, Beijing Key Lab Regenerat Med Orthoped, Key Lab Musculoskeletal Trauma & War Injuries Chin, Beijing 100853, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Baoxiang,Zhang, Wen,Zhang, Fei,et al. Degradable magnesium alloy suture promotes fibrocartilaginous interface regeneration in a rat rotator cuff transosseous repair model[J]. JOURNAL OF MAGNESIUM AND ALLOYS,2024,12(1):384-393. |
| APA | Zhang, Baoxiang.,Zhang, Wen.,Zhang, Fei.,Ning, Chao.,An, Mingyang.,...&Zhang, Qiang.(2024).Degradable magnesium alloy suture promotes fibrocartilaginous interface regeneration in a rat rotator cuff transosseous repair model.JOURNAL OF MAGNESIUM AND ALLOYS,12(1),384-393. |
| MLA | Zhang, Baoxiang,et al."Degradable magnesium alloy suture promotes fibrocartilaginous interface regeneration in a rat rotator cuff transosseous repair model".JOURNAL OF MAGNESIUM AND ALLOYS 12.1(2024):384-393. |
入库方式： OAI收割
来源：金属研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。