Unveiling the transformation products and toxicity of paralytic shellfish toxins under photodegradation and peroxymonosulfate oxidation
文献类型：期刊论文
| 作者 | Zhang, Xiaona1,2,3; Chi, Lianbao1,2,3; Jiang, Kaiqin1,2,3; Wei, Zelong1,2,3; Wang, Mingjiao1,2,3; Yu, Zhiming1,2,3; Song, Xiuxian1,2,3 |
| 刊名 | JOURNAL OF HAZARDOUS MATERIALS
 |
| 出版日期 | 2025-12-05 |
| 卷号 | 500页码:12 |
| 关键词 | Paralytic shellfish toxins Photodegradation Oxidation Transformation products Toxicity evaluation |
| ISSN号 | 0304-3894 |
| DOI | 10.1016/j.jhazmat.2025.140313 |
| 通讯作者 | Song, Xiuxian(songxx@qdio.ac.cn) |
| 英文摘要 | Biotoxins produced by harmful algal blooms (HABs) are a substantial threat to ecosystems and human health. Significantly, paralytic shellfish toxins (PSTs), are prevalent globally and cause significant environmental and economic losses. However, their transformation products (TPs), reaction pathways, and potential risks during photodegradation and oxidative treatment are poorly understood. In this study, the TPs of three typical PSTs subjected to photodegradation and peroxymonosulfate (PMS) oxidation were analyzed by liquid chromatography-high resolution mass spectrometry (LC-HRMS). For saxitoxin (STX), gonyautoxin 2&3 (GTX2&3), and gonyautoxin 1&4 (GTX1&4), seven, nine, and nine TPs were identified under photodegradation and five, four, and six TPs were identified under PMS oxidation. Most TPs underwent structural modifications and mass reductions. Substitution, ring-opening, and nucleophilic reactions are proposed as the main photodegradation pathways. PMS oxidation involves carbamate removal and substitution. In silico prediction demonstrated that photodegradation formed TPs with human toxicity. Conversely, PMS oxidative degradation effectively inhibited highly toxic products formation, reducing the ecological risks to environments. Meanwhile, the growth of Escherichia coli as toxicity test validated low toxicity of the PMS oxidation. Compared with photodegradation, oxidation markedly mitigated the environmental risks associated with PSTs after degradation, offering a novel approach for managing PSTs-related ecological and health risk. |
| WOS关键词 | CARBAMATE PESTICIDES ; DEGRADATION ; RISK ; ANTIBIOTICS ; IRRADIATION ; METABOLITES ; MECHANISM ; EXPOSURE ; KINETICS ; ACID |
| 资助项目 | Intergov-ernmental Innovation Cooperation Project of the Ministry of Science and Technology[2022YFE0136400] ; National Natural Science Foundation of China[42276220] ; National Natural Science Foundation of China[42376210] |
| WOS研究方向 | Engineering ; Environmental Sciences & Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:001620421900006 |
| 出版者 | ELSEVIER |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/204229]  |
| 专题 | 海洋研究所_海洋生态与环境科学重点实验室 |
| 通讯作者 | Song, Xiuxian |
| 作者单位 | 1.Qingdao Marine Sci & Technol Ctr, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Xiaona,Chi, Lianbao,Jiang, Kaiqin,et al. Unveiling the transformation products and toxicity of paralytic shellfish toxins under photodegradation and peroxymonosulfate oxidation[J]. JOURNAL OF HAZARDOUS MATERIALS,2025,500:12. |
| APA | Zhang, Xiaona.,Chi, Lianbao.,Jiang, Kaiqin.,Wei, Zelong.,Wang, Mingjiao.,...&Song, Xiuxian.(2025).Unveiling the transformation products and toxicity of paralytic shellfish toxins under photodegradation and peroxymonosulfate oxidation.JOURNAL OF HAZARDOUS MATERIALS,500,12. |
| MLA | Zhang, Xiaona,et al."Unveiling the transformation products and toxicity of paralytic shellfish toxins under photodegradation and peroxymonosulfate oxidation".JOURNAL OF HAZARDOUS MATERIALS 500(2025):12. |
入库方式： OAI收割
来源：海洋研究所
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