Recent advances in fluorescent glycoconjugate probes for biosensing, bioimaging and targeted photodynamic therapy
文献类型：期刊论文
| 作者 | Han, Hai-Hao1,2,4; Hu, Xi-Le4; He, Xiao-Peng3,4 |
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2025-10-07 |
| 卷号 | 61期号:81页码:15735-15758 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/d5cc03272e |
| 通讯作者 | He, Xiao-Peng(xphe@ecust.edu.cn) |
| 英文摘要 | Fluorescent glycoconjugate probes have emerged as innovative tools for biomedical research, helping to delineate the mechanistic roles of sugars in biological and pathological events. This feature article reviews the recent advances in the development and application of fluorescent glycoconjugate probes since 2021, highlighting their applications for biosensing, targeted imaging and phototherapy. We describe the design principles of these probes, their utilization in the detection and cell imaging of glycosidase activities, and their potential to be developed as theranostic agents. We also discuss the challenges and future directions in this field, including the need for the development of sensitive, selective and biocompatible probes for early diagnosis and treatment of major human diseases such as cancer. |
| WOS关键词 | VIBRATION-INDUCED-EMISSION ; BETA-GLUCURONIDASE ; CANCER ; NANOPARTICLES ; STRATEGIES ; CELLS ; ACTIVATION ; MOLECULES ; BLOCKING ; DELIVERY |
| 资助项目 | National Natural Science Foundation of China[92253306] ; National Natural Science Foundation of China[22477030] ; National Natural Science Foundation of China[22377135] ; National Natural Science Foundation of China[22107029] ; National Natural Science Foundation of China[24DX1400200] ; Science and Technology Commission of Shanghai Municipality[23490711600] ; International Cooperation Program of Shanghai Science and Technology[QNKJ2024010] ; Shanghai Oriental Talents youth Program[23XHYD-20] ; Shanghai Xuhui District Hospital Local Cooperation Project[KF 2402] ; Open Funding Project of the State Key Laboratory of Fine Chemicals, Dalian University of Technology[222201717003] ; Fundamental Research Funds for the Central Universities[B16017] ; Programme of Introducing Talents of Discipline to Universities ; Open Funding Project of the State Key Laboratory of Bioreactor Engineering, State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University[2023-MEKLLC-MS/ZD-00*] ; Ministry of Education Key Laboratory on Signaling Regulation and Targeting Therapy of Liver Cancer (Naval Medical University)[SYS202205] ; Shandong Laboratory Program[tsqn202312305] ; Taishan Scholars Program ; Young Elite Scientists Sponsorship Program by Chinese Chemical Society[2023JCYJ059] ; Fundamental Research Projects of Science & Technology Innovation and Development Plan in Yantai City[2024CXPT028] ; Key R&D Program of Shandong |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001575560200001 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/321531]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | He, Xiao-Peng |
| 作者单位 | 1.Chinese Acad Sci, Mol Imaging Ctr, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 2.Bohai Rim Adv Res Inst Drug Discovery, Shandong Lab Yantai Drug Discovery, Yantai 264117, Shandong, Peoples R China 3.Second Mil Med Univ, Natl Ctr Liver Canc, Int Cooperat Lab Signal Transduct, Eastern Hepatobiliary Surg Inst, Shanghai 200433, Peoples R China 4.East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Ctr Materiobiol & Dynam Chem, Sch Chem & Mol Engn,Key Lab Adv Mat & Joint Int Re, 130 Meilong Rd, Shanghai 200237, Peoples R China |
| 推荐引用方式 GB/T 7714 | Han, Hai-Hao,Hu, Xi-Le,He, Xiao-Peng. Recent advances in fluorescent glycoconjugate probes for biosensing, bioimaging and targeted photodynamic therapy[J]. CHEMICAL COMMUNICATIONS,2025,61(81):15735-15758. |
| APA | Han, Hai-Hao,Hu, Xi-Le,&He, Xiao-Peng.(2025).Recent advances in fluorescent glycoconjugate probes for biosensing, bioimaging and targeted photodynamic therapy.CHEMICAL COMMUNICATIONS,61(81),15735-15758. |
| MLA | Han, Hai-Hao,et al."Recent advances in fluorescent glycoconjugate probes for biosensing, bioimaging and targeted photodynamic therapy".CHEMICAL COMMUNICATIONS 61.81(2025):15735-15758. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。