Ligand-Controlled Acyl and Decarbonylative Sonogashira Cross-Coupling of α,β-Unsaturated Thioesters
文献类型：期刊论文
| 作者 | Sun, Guo-Dong1,4; Huang, Zhi-Cong1,4; Xu, Hui1; Dai, Hui-Xiong1,2,3,4 |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2025-08-22 |
| 卷号 | 27期号:33页码:9179-9183 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/acs.orglett.5c02609 |
| 英文摘要 | A palladium-catalyzed ligand-controlled acyl and decarbonylative Sonogashira reaction of alkenyl thioesters with terminal alkynes was developed. 1,3-Enynes and enynone products were obtained by using 1,3-bis(diphenylphosphino)propane and P(3,5-(CF3)2C6H3)3 as the ligands, respectively. To demonstrate the synthetic utilities, late-stage constructions of 1,3-enyne and enynone skeletons in natural products and drugs were showcased. |
| WOS关键词 | ALKYNYLATION ; ALKYNES ; ARYL |
| 资助项目 | National Natural Science Foundation of China ; Shanghai Institute of Materia Medica ; Chinese Academy of Sciences[22171276] ; Chinese Academy of Sciences[21920102003] ; National Natural Science Foundation of China[17JC1405000] ; National Natural Science Foundation of China[21ZR1475400] ; National Natural Science Foundation of China[23ZR1474400] ; National Natural Science Foundation of China[18431907100] ; Science and Technology Commission of Shanghai Municipality[19XD1424600] ; Program of Shanghai Academic Research Leader |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001545734800001 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/321210]  |
| 专题 | 国家级研究中心_原创新药研究全国重点实验室 |
| 通讯作者 | Xu, Hui; Dai, Hui-Xiong |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China 3.Nanjing Univ Chinese Med, Sch Chinese Mat Med, Nanjing 210023, Jiangsu, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Guo-Dong,Huang, Zhi-Cong,Xu, Hui,et al. Ligand-Controlled Acyl and Decarbonylative Sonogashira Cross-Coupling of α,β-Unsaturated Thioesters[J]. ORGANIC LETTERS,2025,27(33):9179-9183. |
| APA | Sun, Guo-Dong,Huang, Zhi-Cong,Xu, Hui,&Dai, Hui-Xiong.(2025).Ligand-Controlled Acyl and Decarbonylative Sonogashira Cross-Coupling of α,β-Unsaturated Thioesters.ORGANIC LETTERS,27(33),9179-9183. |
| MLA | Sun, Guo-Dong,et al."Ligand-Controlled Acyl and Decarbonylative Sonogashira Cross-Coupling of α,β-Unsaturated Thioesters".ORGANIC LETTERS 27.33(2025):9179-9183. |
入库方式： OAI收割
来源：上海药物研究所
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