Engineering small-molecule phototheranostics for infectious disease imaging and therapy in NIR-II
文献类型：期刊论文
| 作者 | Ding, Qihang2,3; Zhang, Yifan2; Fan, Xianrun2; Zhu, Liming2; Han, Linli2; Li, Tong2; Qian, Kun1; Yin, Gang2; Cheng, Zhen1,4; Mei, Ling2 |
| 刊名 | TRAC-TRENDS IN ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2025-11-01 |
| 卷号 | 192页码:27 |
| 关键词 | Infectious diseases NIR-II Molecular imaging Phototheranostics Small molecules |
| ISSN号 | 0165-9936 |
| DOI | 10.1016/j.trac.2025.118394 |
| 英文摘要 | Infectious diseases remain a significant challenge in the field of public health. In recent years, the second nearinfrared (NIR-II) window fluorescence imaging has shown tremendous potential in the early diagnosis and integrated treatment of infectious diseases, owing to its superior deep-tissue penetration, high-resolution imaging, and low background autofluorescence. Among the various NIR-II fluorescence probes, small organic molecules have emerged as a promising tool for combating pathogens due to their excellent biocompatibility, tunability, and ease of functionalization. This review provides a comprehensive overview of the latest advancements in small-molecule-based NIR-II fluorescence imaging technology for the study of infectious diseases. It highlights molecular design strategies and their applications in the diagnosis and treatment of infections. Additionally, the key challenges, potential opportunities, and future research directions in this burgeoning field are critically analyzed to foster further advancements in this transformative area. |
| WOS关键词 | FLUOROPHORES ; SOCIETY ; AIEGENS ; UPDATE ; NO |
| 资助项目 | China Scholarship Council (CSC)[202106270027] ; National Natural Science Foundation of China[U2267221] ; Shandong Laboratory Program[SYS202205] ; State Key Laboratory of Drug Research[SIMM0120231004] ; Gansu Science and Technology Major Project[23ZDFA014] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB0830300] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001546755400001 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/321240]  |
| 专题 | 国家级研究中心_原创新药研究全国重点实验室 |
| 通讯作者 | Ding, Qihang; Yin, Gang; Cheng, Zhen; Mei, Ling |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Mol Imaging Ctr, State Key Lab Drug Res, Shanghai 201203, Peoples R China 2.Chengdu Univ, Sichuan Ind Inst Antibiot, Engn Res Ctr Pharmaceut & Equipments Sichuan Prov, Sch Pharm, Chengdu 610106, Peoples R China 3.Korea Univ, Dept Chem, Seoul 02841, South Korea 4.Bohai Rim Adv Res Inst Drug Discovery, Shandong Lab Yantai Drug Discovery, Yantai 264117, Shandong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ding, Qihang,Zhang, Yifan,Fan, Xianrun,et al. Engineering small-molecule phototheranostics for infectious disease imaging and therapy in NIR-II[J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY,2025,192:27. |
| APA | Ding, Qihang.,Zhang, Yifan.,Fan, Xianrun.,Zhu, Liming.,Han, Linli.,...&Mei, Ling.(2025).Engineering small-molecule phototheranostics for infectious disease imaging and therapy in NIR-II.TRAC-TRENDS IN ANALYTICAL CHEMISTRY,192,27. |
| MLA | Ding, Qihang,et al."Engineering small-molecule phototheranostics for infectious disease imaging and therapy in NIR-II".TRAC-TRENDS IN ANALYTICAL CHEMISTRY 192(2025):27. |
入库方式： OAI收割
来源：上海药物研究所
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