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Two new naphthopyrones and a new prenylisoflavone from Berchemia lineata

文献类型：期刊论文

作者Li, Ling1,2; Feng, Lin1; Peng, Lihua3; Qiao, Weilin3; Li, Wei1,2; Guo, De-an1,2
刊名PHYTOCHEMISTRY LETTERS
出版日期2026-02-01
卷号71页码:4
关键词Rhamnaceae Berchemia lineata Naphthopyrone Prenylisoflavone NO inhibitory activity
ISSN号1874-3900
DOI10.1016/j.phytol.2026.104111
通讯作者Li, Wei(liwei1@simm.ac.cn) ; Guo, De-an(daguo@simm.ac.cn)
英文摘要Two new naphthopyrones, berchelineatones A and B (1 and 2), together with a new prenylisoflavone (3), were isolated from Berchemia lineata. Their structures were primarily determined by high-resolution mass spectrometry, NMR spectroscopy, and X-ray crystallographic data analysis. Notably, compounds 1 and 2 exhibited potent inhibition on nitric oxide (NO) production induced by lipopolysaccharide (LPS) in RAW264.7 macrophages, with IC50 values of 2.52 and 2.06 mu M, respectively.
资助项目Qi-Huang Chief Scientist Project of the National Administration of Traditional Chinese Medicine
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
语种英语
WOS记录号WOS:001660767100001
出版者ELSEVIER
源URL[http://119.78.100.183/handle/2S10ELR8/322587]  
专题中国科学院上海药物研究所
通讯作者Li, Wei; Guo, De-an
作者单位1.Chinese Acad Sci, Zhongshan Inst Drug Discovery, Shanghai Inst Mat Med, Zhongshan 528400, Peoples R China
2.Zunyi Med Univ, Sch Pharm, Zunyi 563006, Peoples R China
3.Zhongshan Zhongzhi Pharmaceut Grp Co Ltd, Zhongshan 528400, Peoples R China
推荐引用方式
GB/T 7714		 Li, Ling,Feng, Lin,Peng, Lihua,et al. Two new naphthopyrones and a new prenylisoflavone from Berchemia lineata[J]. PHYTOCHEMISTRY LETTERS,2026,71:4.
APA Li, Ling,Feng, Lin,Peng, Lihua,Qiao, Weilin,Li, Wei,&Guo, De-an.(2026).Two new naphthopyrones and a new prenylisoflavone from Berchemia lineata.PHYTOCHEMISTRY LETTERS,71,4.
MLA Li, Ling,et al."Two new naphthopyrones and a new prenylisoflavone from Berchemia lineata".PHYTOCHEMISTRY LETTERS 71(2026):4.

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来源：上海药物研究所

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