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Chemoenzymatic synthesis of sulfated O-glycopeptides from human CD34

文献类型：期刊论文

作者Jiang, Yinyu3,4; Du, Qi1,5; Wu, Fengzhuo4; Zhang, Wei4; Ma, Yuan3; Xu, Zhuojia3; Li, Zhonghua1,5; Ma, Wenjing2,3; Li, Tiehai3,4
刊名CHEMICAL COMMUNICATIONS
出版日期2026-02-26
卷号62期号:16页码:4843-4846
ISSN号1359-7345
DOI10.1039/d6cc00114a
通讯作者Li, Zhonghua(zhonghua_@fudan.edu.cn) ; Ma, Wenjing(mwj@xjtu.edu.cn) ; Li, Tiehai(tiehaili@simm.ac.cn)
英文摘要O-Glycosylation is a key modulator of CD34 biofunction. To investigate the distinct roles of different glycoform modifications, we report an efficient chemoenzymatic strategy to rapidly assemble a library of CD34 O-glycopeptides bearing sulfated and sialylated glycan variants, enabling the elucidation of how specific glycan modifications govern molecular recognition events.
WOS关键词L-SELECTIN ; BINDING ; RECOGNITION ; PEPTIDE ; LECTINS ; ENZYMES ; ACIDS
资助项目National Natural Science Foundation of China[22377134] ; National Natural Science Foundation of China[22507132] ; National Natural Science Foundation of China[22307020] ; Strategic Priority Research Program of CAS[XDB1060000] ; Shenzhen Medical Research Fund[B2402031]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:001689100500001
出版者ROYAL SOC CHEMISTRY
源URL[http://119.78.100.183/handle/2S10ELR8/322999]  
专题中国科学院上海药物研究所
通讯作者Li, Zhonghua; Ma, Wenjing; Li, Tiehai
作者单位1.Fudan Univ, Sch Basic Med Sci, Dept Biochem & Mol Biol, NHC Key Lab Glycoconjugates Res, Shanghai 200032, Peoples R China
2.Xi An Jiao Tong Univ, Sch Pharm, Xian 710061, Shaanxi, Peoples R China
3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Chem Biol, Shanghai 201203, Peoples R China
4.Nanjing Univ Chinese Med, Sch Chinese Mat Med, Nanjing 210023, Peoples R China
5.Fudan Univ, Zhongshan Hosp, Dept Hepatobiliary Oncol, Shanghai 200032, Peoples R China
推荐引用方式
GB/T 7714		 Jiang, Yinyu,Du, Qi,Wu, Fengzhuo,et al. Chemoenzymatic synthesis of sulfated O-glycopeptides from human CD34[J]. CHEMICAL COMMUNICATIONS,2026,62(16):4843-4846.
APA Jiang, Yinyu.,Du, Qi.,Wu, Fengzhuo.,Zhang, Wei.,Ma, Yuan.,...&Li, Tiehai.(2026).Chemoenzymatic synthesis of sulfated O-glycopeptides from human CD34.CHEMICAL COMMUNICATIONS,62(16),4843-4846.
MLA Jiang, Yinyu,et al."Chemoenzymatic synthesis of sulfated O-glycopeptides from human CD34".CHEMICAL COMMUNICATIONS 62.16(2026):4843-4846.

入库方式： OAI收割

来源：上海药物研究所

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