Preparation, characterization and MRI application of carboxymethyl dextran coated magnetic nanoparticles
文献类型：期刊论文
| 作者 | Liu, G.2; Hong, R. Y.1,2,3,4,5; Guo, L.6; Li, Y. G.6; Li, H. Z.4 |
| 刊名 | APPLIED SURFACE SCIENCE
 |
| 出版日期 | 2011-05-15 |
| 卷号 | 257期号:15页码:6711-6717 |
| 关键词 | Carboxymethyl dextran Monochloroacetic acid MRI Magnetic nanoparticle |
| ISSN号 | 0169-4332 |
| 通讯作者 | Hong, RY |
| 英文摘要 | Superparamagnetic nanoparticles functionalized with carboxymethyl dextran (CM-dextran) were synthesized by a two-step method. First, the magnetic nanoparticles (MNPs) coated with dextran (M(w) approximate to 20000) were prepared by co-precipitation of Fe(2+) and Fe(3+) ions. Then, dextran on the surface of MNPs reacted with monochloroacetic acid (MCA) in alkaline condition. The influences of temperature and reactant concentration on the amount of -COOH on the surface of nanoparticles were systematically studied. The obtained MNPs coated with CM-dextran were stable over the entire range of pH and NaCl concentration. The MRI experiment indicated that the CM-dextran MNPs could potentially be used as MRI contrast agents for magnetic resonance molecular imaging. (C) 2011 Elsevier B. V. All rights reserved. |
| WOS标题词 | Science & Technology ; Physical Sciences ; Technology |
| 类目[WOS] | Chemistry, Physical ; Materials Science, Coatings & Films ; Physics, Applied ; Physics, Condensed Matter |
| 研究领域[WOS] | Chemistry ; Materials Science ; Physics |
| 关键词[WOS] | IRON-OXIDE NANOPARTICLES ; FEPT NANOPARTICLES ; CONTRAST AGENTS ; GENE DELIVERY ; IN-VITRO ; PARTICLES ; POLYMER ; FLUIDS ; VIVO |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000289512500063 |
| 公开日期 | 2013-11-06 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/5053]  |
| 专题 | 过程工程研究所_多相复杂系统国家重点实验室 |
| 作者单位 | 1.Soochow Univ, Chem Engn Dept 199, SIP, Coll Chem Chem Engn & Mat Sci, Suzhou 215123, Jiangsu, Peoples R China 2.Soochow Univ, SIP, Key Lab Organ Synth Jiangsu Prov, Suzhou 215123, Jiangsu, Peoples R China 3.Fuzhou Univ, Coll Chem & Chem Engn, Fuzhou 350002, Peoples R China 4.Chinese Acad Sci, State Key Lab Multiphase Complex Syst, Inst Proc Engn, Beijing 100080, Peoples R China 5.Ningxia Univ, Coll Chem & Chem Engn, Yinchuan 750021, Peoples R China 6.Soochow Univ, MRI Div, Affiliated Hosp 1, Suzhou 215007, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, G.,Hong, R. Y.,Guo, L.,et al. Preparation, characterization and MRI application of carboxymethyl dextran coated magnetic nanoparticles[J]. APPLIED SURFACE SCIENCE,2011,257(15):6711-6717. |
| APA | Liu, G.,Hong, R. Y.,Guo, L.,Li, Y. G.,&Li, H. Z..(2011).Preparation, characterization and MRI application of carboxymethyl dextran coated magnetic nanoparticles.APPLIED SURFACE SCIENCE,257(15),6711-6717. |
| MLA | Liu, G.,et al."Preparation, characterization and MRI application of carboxymethyl dextran coated magnetic nanoparticles".APPLIED SURFACE SCIENCE 257.15(2011):6711-6717. |
入库方式： OAI收割
来源：过程工程研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。