Integrated bioprocess for high-efficiency production of succinic acid in an expanded-bed adsorption system
文献类型：期刊论文
| 作者 | Li, Qiang1; Wang, Dan2; Hu, Guangyu3; Xing, Jianmin1; Su, Zhiguo1 |
| 刊名 | BIOCHEMICAL ENGINEERING JOURNAL
 |
| 出版日期 | 2011-10-15 |
| 卷号 | 56期号:3页码:150-157 |
| 关键词 | Succinic acid Expanded-bed adsorption Bioreactors Process integration Product inhibition Bioconversion |
| ISSN号 | 1369-703X |
| 通讯作者 | Xing, JM |
| 英文摘要 | An integrated fermentation process for the production of succinic acid by Actinobacillus succinogenes at high titer, yield and productivity was developed by applying in situ product removal (ISPR) strategy. The ISPR process was conducted by a coupled expanded-bed adsorption (EBA) system. The novel approach during the product inhibitory period of microbial fermentation enhanced the cell growth of A. succinogenes from 48 h to 126 h, and significantly increased succinic acid production up to the final titer of 145.2 g l(-1) with an average yield of 0.52 g g(-1), and productivity of 1.3 g l(-1) h(-1). The maximum yield and productivity reached 0.76 g g(-1) and 2.58 gl(-1) h(-1), respectively after the first ISPR operation cycle. ISPR process with EBA leads to the production of succinct acid via fermentation economically feasible. (C) 2011 Elsevier B.V. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Technology |
| 类目[WOS] | Biotechnology & Applied Microbiology ; Engineering, Chemical |
| 研究领域[WOS] | Biotechnology & Applied Microbiology ; Engineering |
| 关键词[WOS] | ESCHERICHIA-COLI ; MANNHEIMIA-SUCCINICIPRODUCENS ; FERMENTATION ; REMOVAL |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000295197000007 |
| 公开日期 | 2013-10-30 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/4582]  |
| 专题 | 过程工程研究所_生化工程国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Natl Key Lab Biochem Engn, Inst Proc Engn, Beijing 100190, Peoples R China 2.Chongqing Univ, Coll Chem & Chem Engn, Chongqing 400044, Peoples R China 3.China Studies Publ Policy & Management Consulting, Beijing 100084, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Qiang,Wang, Dan,Hu, Guangyu,et al. Integrated bioprocess for high-efficiency production of succinic acid in an expanded-bed adsorption system[J]. BIOCHEMICAL ENGINEERING JOURNAL,2011,56(3):150-157. |
| APA | Li, Qiang,Wang, Dan,Hu, Guangyu,Xing, Jianmin,&Su, Zhiguo.(2011).Integrated bioprocess for high-efficiency production of succinic acid in an expanded-bed adsorption system.BIOCHEMICAL ENGINEERING JOURNAL,56(3),150-157. |
| MLA | Li, Qiang,et al."Integrated bioprocess for high-efficiency production of succinic acid in an expanded-bed adsorption system".BIOCHEMICAL ENGINEERING JOURNAL 56.3(2011):150-157. |
入库方式： OAI收割
来源：过程工程研究所
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