Effect of acrylic acid weight percentage on the pore size in poly(N-Isopropyl acrylamide-co-acrylic acid) microspheres
文献类型：期刊论文
| 作者 | Si, Tianbao1,2; Wang, Yuxia1; Wei, Wei1,2; Lv, Piping1,2; Ma, Guanghui1; Su, Zhiguo1 |
| 刊名 | REACTIVE & FUNCTIONAL POLYMERS
 |
| 出版日期 | 2011-07-01 |
| 卷号 | 71期号:7页码:728-735 |
| 关键词 | P(NIPAM-co-AAc) microsphere Pore size Membrane emulsification Supercritical drying Phase separation |
| ISSN号 | 1381-5148 |
| 通讯作者 | Wang, YX |
| 英文摘要 | In this article, a simple way to control pore size in monodispersed poly(N-Isopropyl acrylamide-co-acrylic acid) [P(NIPAM-co-AAc)] microspheres just by changing the acrylic acid wt.% in the formula was developed. The monodispersed P(NIPAM-co-AAc) microspheres with functionalized carboxyl groups were successfully prepared by Shirasu porous glass (SPG) membrane emulsification technique at room temperature. The microspheres were dried by supercritical drying (SCD), lyophilization and vacuum drying, separately. It was observed that SCD was an effective drying method to maintain the morphologies of the microspheres. Scanning electron microscopy (SEM), confocal laser scanning microscope (CLSM), and porosity analyzer results showed that the P(NIPAM-co-AAc) microspheres contained abundant slit-like mesoporous structure with pore size from 2 nm to 50 nm. The increase of AAc wt.% would increase the percentage of mesopores and micropores in the microspheres. P(NIPAM-co-AAc) microspheres with specific pore size can be obtained by simply changing the acrylic acid wt.% in the formula. Such temperature-/pH-sensitive microspheres with controllable pore size were expected to meet various requirements in different bioapplications, such as drug delivery and enzyme immobilization. (C) 2011 Elsevier Ltd. All rights reserved. |
| WOS标题词 | Science & Technology ; Physical Sciences ; Technology |
| 类目[WOS] | Chemistry, Applied ; Engineering, Chemical ; Polymer Science |
| 研究领域[WOS] | Chemistry ; Engineering ; Polymer Science |
| 关键词[WOS] | N-ISOPROPYLACRYLAMIDE ; SURFACE-AREA ; DRUG-DELIVERY ; HEAVY-METAL ; HYDROGEL ; SEPARATION ; NETWORKS ; RELEASE ; DESIGN ; CHROMATOGRAPHY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000292126500007 |
| 公开日期 | 2013-11-05 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/4863]  |
| 专题 | 过程工程研究所_生化工程国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Si, Tianbao,Wang, Yuxia,Wei, Wei,et al. Effect of acrylic acid weight percentage on the pore size in poly(N-Isopropyl acrylamide-co-acrylic acid) microspheres[J]. REACTIVE & FUNCTIONAL POLYMERS,2011,71(7):728-735. |
| APA | Si, Tianbao,Wang, Yuxia,Wei, Wei,Lv, Piping,Ma, Guanghui,&Su, Zhiguo.(2011).Effect of acrylic acid weight percentage on the pore size in poly(N-Isopropyl acrylamide-co-acrylic acid) microspheres.REACTIVE & FUNCTIONAL POLYMERS,71(7),728-735. |
| MLA | Si, Tianbao,et al."Effect of acrylic acid weight percentage on the pore size in poly(N-Isopropyl acrylamide-co-acrylic acid) microspheres".REACTIVE & FUNCTIONAL POLYMERS 71.7(2011):728-735. |
入库方式： OAI收割
来源：过程工程研究所
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