Effect of bovine serum albumin on the micellization of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymers in aqueous solutions by fluorescence spectroscopy
文献类型：期刊论文
| 作者 | Guo Chen; Wang Jing; Liang Xiangfeng; Zheng Lili; Liu Huizhou |
| 刊名 | SCIENCE IN CHINA SERIES B-CHEMISTRY
 |
| 出版日期 | 2006-12-01 |
| 卷号 | 49期号:6页码:541-549 |
| 关键词 | block copolymer bovine serum albumin micelle fluorescence spectroscopy |
| ISSN号 | 1006-9291 |
| 其他题名 | Sci. China Ser. B-Chem. |
| 中文摘要 | Effect of bovine serum albumin (BSA) on the temperature-dependent association behavior of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) block copolymers was investigated using pyrene fluorescence spectroscopy. The critical micellization temperature (CMT) of pluronics in aqueous solution was increased by the addition of BSA. A closed association model was used to obtain the standard free energies (Delta G(0)), enthalpies (Delta H-0), and entropies (Delta S-0) of micellization. The standard enthalpy and entropy of micellization for pluronic polymers in water were decreased with an increase of the BSA content. The more PPO component in the pluronic polymer, the higher the changed values of micellization enthalpy and entropy. The hydrophobic part of the pluronics, PPO, was responsible for the interaction between pluronics and BSA. Hydrophobic interaction between PPO and BSA was correlated to the alternation of the PPO-PPO interaction by the addition of BSA, which would shift the CMT toward higher temperature and alter the thermodynamic parameters of micellization for pluronics in aqueous solutions. |
| 英文摘要 | Effect of bovine serum albumin (BSA) on the temperature-dependent association behavior of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) block copolymers was investigated using pyrene fluorescence spectroscopy. The critical micellization temperature (CMT) of pluronics in aqueous solution was increased by the addition of BSA. A closed association model was used to obtain the standard free energies (Delta G(0)), enthalpies (Delta H-0), and entropies (Delta S-0) of micellization. The standard enthalpy and entropy of micellization for pluronic polymers in water were decreased with an increase of the BSA content. The more PPO component in the pluronic polymer, the higher the changed values of micellization enthalpy and entropy. The hydrophobic part of the pluronics, PPO, was responsible for the interaction between pluronics and BSA. Hydrophobic interaction between PPO and BSA was correlated to the alternation of the PPO-PPO interaction by the addition of BSA, which would shift the CMT toward higher temperature and alter the thermodynamic parameters of micellization for pluronics in aqueous solutions. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Chemistry, Multidisciplinary |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | TEMPERATURE-DEPENDENT MICELLIZATION ; ANGLE NEUTRON-SCATTERING ; MICELLAR 2-PHASE SYSTEMS ; TRIBLOCK COPOLYMER ; STRUCTURAL-PROPERTIES ; PHASE-BEHAVIOR ; DRUG-DELIVERY ; PROTEIN ; SURFACTANTS ; MICROENVIRONMENT |
| 收录类别 | SCI |
| 原文出处 | |
| 语种 | 英语 |
| WOS记录号 | WOS:000244104200009 |
| 公开日期 | 2013-10-24 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/3955]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | Grad Univ Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Lab Separat Sci & Engn, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Guo Chen,Wang Jing,Liang Xiangfeng,et al. Effect of bovine serum albumin on the micellization of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymers in aqueous solutions by fluorescence spectroscopy[J]. SCIENCE IN CHINA SERIES B-CHEMISTRY,2006,49(6):541-549. |
| APA | Guo Chen,Wang Jing,Liang Xiangfeng,Zheng Lili,&Liu Huizhou.(2006).Effect of bovine serum albumin on the micellization of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymers in aqueous solutions by fluorescence spectroscopy.SCIENCE IN CHINA SERIES B-CHEMISTRY,49(6),541-549. |
| MLA | Guo Chen,et al."Effect of bovine serum albumin on the micellization of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymers in aqueous solutions by fluorescence spectroscopy".SCIENCE IN CHINA SERIES B-CHEMISTRY 49.6(2006):541-549. |
入库方式： OAI收割
来源：过程工程研究所
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