Metabolic studies on the total phenolic acids from the roots of Salivia miltiorrhiza in rats
文献类型：期刊论文
| 作者 | Zhang, JL; He, Y; Cui, M; Li, L; Yu, HL; Zhang, GF; Guo, D |
| 刊名 | BIOMEDICAL CHROMATOGRAPHY
 |
| 出版日期 | 2005 |
| 卷号 | 19期号:1页码:51-59 |
| 关键词 | Salvia miltiorrhiza total phenolic acids metabolisms HPLC-UV and HPLC-MS analysis |
| ISSN号 | 0269-3879 |
| 其他题名 | Biomed. Chromatogr. |
| 中文摘要 | Phenolic acids are the main active constituents of Salvia miltiorrhiza Bunge. The metabolism of total phenolic acids from the roots of Salvia miltiorrhiza in rats was investigated. A sample preparation method combining the solid-phase extraction with liquid-liquid extraction was established to separate metabolites from the biological matrix. HPLC-UV and HPLC-MS methods were employed to analyze the metabolites. Five metabolites (M1-M5) were identified by HPLC-MS analysis and comparison with those of the reference standards. The five metabolites were characterized as danshensu (M1), caffeic acid (M2), ferulic acid (M3), isoferulic acid (M4) and methylized ferulic acid (M5), respectively. The possible metabolic pathway of the phenolic acids is proposed. Copyright (C) 2004 John Wiley Sons, Ltd. |
| 英文摘要 | Phenolic acids are the main active constituents of Salvia miltiorrhiza Bunge. The metabolism of total phenolic acids from the roots of Salvia miltiorrhiza in rats was investigated. A sample preparation method combining the solid-phase extraction with liquid-liquid extraction was established to separate metabolites from the biological matrix. HPLC-UV and HPLC-MS methods were employed to analyze the metabolites. Five metabolites (M1-M5) were identified by HPLC-MS analysis and comparison with those of the reference standards. The five metabolites were characterized as danshensu (M1), caffeic acid (M2), ferulic acid (M3), isoferulic acid (M4) and methylized ferulic acid (M5), respectively. The possible metabolic pathway of the phenolic acids is proposed. Copyright (C) 2004 John Wiley Sons, Ltd. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences |
| 类目[WOS] | Biochemical Research Methods ; Biochemistry & Molecular Biology ; Chemistry, Analytical ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Chemistry ; Pharmacology & Pharmacy |
| 收录类别 | SCI |
| 原文出处 | |
| 语种 | 英语 |
| WOS记录号 | WOS:000227233400009 |
| 公开日期 | 2013-10-25 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/4192]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | 1.Peking Univ, Sch Pharmaceut Sci, Beijing 100083, Peoples R China 2.Peking Univ, Modern Res Ctr Tradit Chinese Med, Beijing 100083, Peoples R China 3.Chinese Acad Sci, Inst Proc Engn, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, JL,He, Y,Cui, M,et al. Metabolic studies on the total phenolic acids from the roots of Salivia miltiorrhiza in rats[J]. BIOMEDICAL CHROMATOGRAPHY,2005,19(1):51-59. |
| APA | Zhang, JL.,He, Y.,Cui, M.,Li, L.,Yu, HL.,...&Guo, D.(2005).Metabolic studies on the total phenolic acids from the roots of Salivia miltiorrhiza in rats.BIOMEDICAL CHROMATOGRAPHY,19(1),51-59. |
| MLA | Zhang, JL,et al."Metabolic studies on the total phenolic acids from the roots of Salivia miltiorrhiza in rats".BIOMEDICAL CHROMATOGRAPHY 19.1(2005):51-59. |
入库方式： OAI收割
来源：过程工程研究所
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