Modelling the production of nisin by Lactococcus lactis in fed-batch culture
文献类型：期刊论文
| 作者 | Lv, WH; Zhang, XY; Cong, W |
| 刊名 | APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
 |
| 出版日期 | 2005-08-01 |
| 卷号 | 68期号:3页码:322-326 |
| 关键词 | bacteriocin production acid fermentation growth ph kinetics |
| ISSN号 | 0175-7598 |
| 其他题名 | Appl. Microbiol. Biotechnol. |
| 中文摘要 | Nisin production in batch culture and fed-batch cultures ( sucrose feeding rates were 6, 7, 8, and 10 g l(-1) h(-1), respectively) by Lactococcus lactis subsp. lactis ATCC 11454 was investigated. Nisin production showed primary metabolite kinetics, and could be improved apparently by altering the feeding strategy. The nisin titer reached its maximum, 4,185 IU ml(-1), by constant addition of sucrose at a feeding rate of 7 g l(-1) h(-1); an increase in 58% over that of the batch culture ( 2,658 IU ml(-1)). Nisin biosynthesis was affected strongly by the residual sucrose concentration during the feeding. Finally, a mathematical model was developed to simulate the cell growth, sucrose consumption, lactic acid production and nisin production. The model was able to describe the fermentation process in all cases. |
| 英文摘要 | Nisin production in batch culture and fed-batch cultures ( sucrose feeding rates were 6, 7, 8, and 10 g l(-1) h(-1), respectively) by Lactococcus lactis subsp. lactis ATCC 11454 was investigated. Nisin production showed primary metabolite kinetics, and could be improved apparently by altering the feeding strategy. The nisin titer reached its maximum, 4,185 IU ml(-1), by constant addition of sucrose at a feeding rate of 7 g l(-1) h(-1); an increase in 58% over that of the batch culture ( 2,658 IU ml(-1)). Nisin biosynthesis was affected strongly by the residual sucrose concentration during the feeding. Finally, a mathematical model was developed to simulate the cell growth, sucrose consumption, lactic acid production and nisin production. The model was able to describe the fermentation process in all cases. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Biotechnology & Applied Microbiology |
| 研究领域[WOS] | Biotechnology & Applied Microbiology |
| 关键词[WOS] | BACTERIOCIN PRODUCTION ; ACID FERMENTATION ; GROWTH ; PH ; KINETICS |
| 收录类别 | SCI |
| 原文出处 | |
| 语种 | 英语 |
| WOS记录号 | WOS:000231220900006 |
| 公开日期 | 2013-10-25 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/4199]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | Chinese Acad Sci, Grad Sch, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lv, WH,Zhang, XY,Cong, W. Modelling the production of nisin by Lactococcus lactis in fed-batch culture[J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2005,68(3):322-326. |
| APA | Lv, WH,Zhang, XY,&Cong, W.(2005).Modelling the production of nisin by Lactococcus lactis in fed-batch culture.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,68(3),322-326. |
| MLA | Lv, WH,et al."Modelling the production of nisin by Lactococcus lactis in fed-batch culture".APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 68.3(2005):322-326. |
入库方式： OAI收割
来源：过程工程研究所
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