Investigation of pH sensitivity of poly(acrylic acid-co-acrylamide) hydrogel
文献类型：期刊论文
| 作者 | Zhou, XJ; Weng, LH; Chen, Q; Zhang, JM; Shen, DY; Li, ZC; Shao, MJ; Xu, J |
| 刊名 | POLYMER INTERNATIONAL
 |
| 出版日期 | 2003-07-01 |
| 卷号 | 52期号:7页码:1153-1157 |
| 关键词 | pH sensitivity hydrogel upper critical solution temperature poly(acrylic acid-co-acrylamide) |
| ISSN号 | 0959-8103 |
| 其他题名 | Polym. Int. |
| 中文摘要 | It was found that the upper critical solution temperature (UCST) of poly(acrylic acid-co-acrylamide) hydrogel decreases with increase in pH. The UCST of samples equilibrated in a buffer at pH 2.5 was 33.7 degreesC, whereas it shifted to below 0 degreesC when swollen in buffers above pH 10. FT-IR showed that COOH group of acrylic acid ionized gradually in alkaline media. The morphology change of the hydrogel swollen in different buffers was studied by environmental scanning electron microscopy (ESEM). ESEM images showed that the pore size of the sample increased with increase in pH, and in strongly basic media the three-dimensional network was replaced by a `sausage-like' or `desert-like' structure. A study of the pH-dependent release of cefazolin sodium was also carried out. (C) 2003 Society of Chemical Industry. |
| 英文摘要 | It was found that the upper critical solution temperature (UCST) of poly(acrylic acid-co-acrylamide) hydrogel decreases with increase in pH. The UCST of samples equilibrated in a buffer at pH 2.5 was 33.7 degreesC, whereas it shifted to below 0 degreesC when swollen in buffers above pH 10. FT-IR showed that COOH group of acrylic acid ionized gradually in alkaline media. The morphology change of the hydrogel swollen in different buffers was studied by environmental scanning electron microscopy (ESEM). ESEM images showed that the pore size of the sample increased with increase in pH, and in strongly basic media the three-dimensional network was replaced by a `sausage-like' or `desert-like' structure. A study of the pH-dependent release of cefazolin sodium was also carried out. (C) 2003 Society of Chemical Industry. |
| WOS标题词 | Science & Technology ; Physical Sciences |
| 类目[WOS] | Polymer Science |
| 研究领域[WOS] | Polymer Science |
| 关键词[WOS] | ACID-CO-2-HYDROXYETHYL METHACRYLATE) HYDROGELS ; INTERPENETRATING POLYMER NETWORKS ; IONIZABLE DRUGS ; ACID) ; RELEASE ; TEMPERATURE ; TRANSPORT ; PROTEINS ; DELIVERY |
| 收录类别 | SCI |
| 原文出处 | |
| 语种 | 英语 |
| WOS记录号 | WOS:000183923600015 |
| 公开日期 | 2013-11-08 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/5304]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, State Key Lab Polymer Phys & Chem, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Inst Proc Engn, Multiphase React Lab, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, XJ,Weng, LH,Chen, Q,et al. Investigation of pH sensitivity of poly(acrylic acid-co-acrylamide) hydrogel[J]. POLYMER INTERNATIONAL,2003,52(7):1153-1157. |
| APA | Zhou, XJ.,Weng, LH.,Chen, Q.,Zhang, JM.,Shen, DY.,...&Xu, J.(2003).Investigation of pH sensitivity of poly(acrylic acid-co-acrylamide) hydrogel.POLYMER INTERNATIONAL,52(7),1153-1157. |
| MLA | Zhou, XJ,et al."Investigation of pH sensitivity of poly(acrylic acid-co-acrylamide) hydrogel".POLYMER INTERNATIONAL 52.7(2003):1153-1157. |
入库方式： OAI收割
来源：过程工程研究所
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