Artemisinin production by adventitious shoots of Artemisia annua in a novel mist bioreactor
文献类型：期刊论文
| 作者 | Lii, CZ; Wang, YC; Kang, XZ; Fan, OY; Ye, HC; Li, GF |
| 刊名 | ACTA BOTANICA SINICA
 |
| 出版日期 | 1999-05-01 |
| 卷号 | 41期号:5页码:524-527 |
| 关键词 | Artemisia annua mist bioreactor adventitious shoot artemisinin |
| ISSN号 | 0577-7496 |
| 其他题名 | Acta Bot. Sin. |
| 中文摘要 | A novel ultrasonic inner-loop bioreactor was used for artemisinin production by adventitious shoots in a multiplate culture of Artemisia annua L. The bioreactor was designed to allow the nutrient mist to uprise along a concentric draught-cylinder until it overflows from the top opening and the side-holes of the central tube downward and out of the annulus, so that the nutrient mist can be fulfilled in the bioreactor within 2 similar to 3 minutes. Under the misting cycles of every 3-minute misting in every 90 minute interval, artemisinin production reached totally 46.9 mg DW/L of culture medium at an airflow rate of 0.5 L/min for 25 d of culture in batches. The product amounted 2.9 and 3.2 folds of those obtained from culturing in solid medium and in shaking flasks respectively. |
| 英文摘要 | A novel ultrasonic inner-loop bioreactor was used for artemisinin production by adventitious shoots in a multiplate culture of Artemisia annua L. The bioreactor was designed to allow the nutrient mist to uprise along a concentric draught-cylinder until it overflows from the top opening and the side-holes of the central tube downward and out of the annulus, so that the nutrient mist can be fulfilled in the bioreactor within 2 similar to 3 minutes. Under the misting cycles of every 3-minute misting in every 90 minute interval, artemisinin production reached totally 46.9 mg DW/L of culture medium at an airflow rate of 0.5 L/min for 25 d of culture in batches. The product amounted 2.9 and 3.2 folds of those obtained from culturing in solid medium and in shaking flasks respectively. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
| 关键词[WOS] | QINGHAOSU ARTEMISININ ; ANTIMALARIAL DRUG ; CULTURES |
| 收录类别 | SCI |
| 原文出处 | |
| 语种 | 英语 |
| WOS记录号 | WOS:000082558200016 |
| 公开日期 | 2013-11-15 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/5861]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem Met, State Key Lab Biochem Engn, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Inst Bot, Beijing 100093, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lii, CZ,Wang, YC,Kang, XZ,et al. Artemisinin production by adventitious shoots of Artemisia annua in a novel mist bioreactor[J]. ACTA BOTANICA SINICA,1999,41(5):524-527. |
| APA | Lii, CZ,Wang, YC,Kang, XZ,Fan, OY,Ye, HC,&Li, GF.(1999).Artemisinin production by adventitious shoots of Artemisia annua in a novel mist bioreactor.ACTA BOTANICA SINICA,41(5),524-527. |
| MLA | Lii, CZ,et al."Artemisinin production by adventitious shoots of Artemisia annua in a novel mist bioreactor".ACTA BOTANICA SINICA 41.5(1999):524-527. |
入库方式： OAI收割
来源：过程工程研究所
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