Casein Phosphopeptide-Biofunctionalized Graphene Biocomposite for Hydroxyapatite Biomimetic Mineralization
文献类型：期刊论文
| 作者 | Fan ZJ(范增杰)1,2; Wang JQ(王金清)1 ; Wang ZF(王赵峰)1; Li ZP(李章朋)1; Qiu YN(邱宜农)3; Wang HG(王宏刚)1; Xu Y(许晔)1,2; Niu LY(牛棱渊)1,2; Gong PW(公培伟)1,2; Yang SR(杨生荣)1
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| 刊名 | Journal of Physical Chemistry C
 |
| 出版日期 | 2013 |
| 卷号 | 117期号:20页码:10375-10382 |
| ISSN号 | 1932-7447 |
| 通讯作者 | 王金清 ; 杨生荣 |
| 英文摘要 | Casein phosphopeptides (CPPs) with abundant phosphoserine clusters can mediate hydroxyapatite (HA) nucleation and growth. In this work, a new type of CPPsbiofuctionalized graphene composite was synthesized by amidation reaction between CPPs and carboxyalated grapheme (CGO). When immersed in stimulated body fluid (1.5 × SBF) at 37 °C for different periods, the CPPs layer on the composite facilitated efficient interaction between the CGO surface and mineral ions, which promoted HA nanoparticle formation and shortened mineralization time in comparison with pristine CGO. The synthesis of the composite mimicked the natural biomineralization of bone, demonstrating that CPPs can effectively improve the bioactivity of graphene and be useful for HA formation. The presented biocomposite may have potential biomedical applications in different areas. |
| 学科主题 | 材料科学与物理化学 |
| 收录类别 | SCI |
| 资助信息 | the National Natural Science Foundation of China (grant nos. 51075384;51205385);“Top Hundred Talents Program” of Chinese Academy of Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000319649400019 |
| 公开日期 | 2013-12-03 |
| 源URL | [http://210.77.64.217/handle/362003/4345]  |
| 专题 | 兰州化学物理研究所_固体润滑国家重点实验室 兰州化学物理研究所_先进润滑与防护材料研究发展中心 |
| 作者单位 | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou 730000, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100080, Peoples R China 3.Lanzhou Command PLA, Lanzhou Gen Hosp, Dept Stomatol, Lanzhou 730050, Peoples R China |
| 推荐引用方式 GB/T 7714 | Fan ZJ,Wang JQ,Wang ZF,et al. Casein Phosphopeptide-Biofunctionalized Graphene Biocomposite for Hydroxyapatite Biomimetic Mineralization[J]. Journal of Physical Chemistry C,2013,117(20):10375-10382. |
| APA | Fan ZJ.,Wang JQ.,Wang ZF.,Li ZP.,Qiu YN.,...&Yang SR.(2013).Casein Phosphopeptide-Biofunctionalized Graphene Biocomposite for Hydroxyapatite Biomimetic Mineralization.Journal of Physical Chemistry C,117(20),10375-10382. |
| MLA | Fan ZJ,et al."Casein Phosphopeptide-Biofunctionalized Graphene Biocomposite for Hydroxyapatite Biomimetic Mineralization".Journal of Physical Chemistry C 117.20(2013):10375-10382. |
入库方式： OAI收割
来源：兰州化学物理研究所
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