Measurement of acid dissociation constants and ionic mobilities of 3-nitro-tyrosine and 3-chloro-tyrosine by capillary zone electrophoresis
文献类型：期刊论文
| 作者 | Ren HX(任海霞)1,2 ; Wang LC(王立成)1; Wang XS(王旭生)1; Liu X(刘霞)1; Jiang SX(蒋生祥)1; Jiang SX(蒋生祥)
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| 刊名 | Journal of Pharmaceutical and Biomedical Analysis
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| 出版日期 | 2013 |
| 卷号 | 77页码:83-87 |
| 关键词 | Absolute ionic mobility Acidity constant Amino acid Cationic coating Hydrodynamic radius |
| ISSN号 | 0731-7085 |
| 通讯作者 | 蒋生祥 |
| 英文摘要 | The ionization constant (pKa) and limiting ionic mobility of 3-chlorotyrosine (CT) and 3-nitrotyrosine (NT) were determined in capillary zone electrophoresis (CZE) in a wide pH range. Measurements were carried out in a poly(ionic liquid) (PIL) modified capillary at a low pH (1.80–4.00) and a bare fused capillary at an upper pH (3.00–11.00). Electrostatic interaction between analytes and inner wall was suppressed dramatically. Furthermore, parameters usually empirically assumed were calculated from a simple theoretical model. Besides pKa and limiting ionic mobility, diameter of the hydrated ion was calculated as well. The former were inserted into the database of Peakmaster software, whose predictions led to satisfactory agreement with experimental runs. |
| 学科主题 | 分析化学与药物化学 |
| 收录类别 | SCI |
| 资助信息 | Natural Science Foundation of Gansu Province, China (No. 0803RJZ017);the National Science Foundation of China (Nos. 21175143;201105107) |
| 语种 | 英语 |
| WOS记录号 | WOS:000316306000014 |
| 公开日期 | 2013-12-10 |
| 源URL | [http://210.77.64.217/handle/362003/4620]  |
| 专题 | 兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| 通讯作者 | Jiang SX(蒋生祥) |
| 作者单位 | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, CAS Key Lab Nat Med Gansu Prov, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ren HX,Wang LC,Wang XS,et al. Measurement of acid dissociation constants and ionic mobilities of 3-nitro-tyrosine and 3-chloro-tyrosine by capillary zone electrophoresis[J]. Journal of Pharmaceutical and Biomedical Analysis,2013,77:83-87. |
| APA | Ren HX,Wang LC,Wang XS,Liu X,Jiang SX,&蒋生祥.(2013).Measurement of acid dissociation constants and ionic mobilities of 3-nitro-tyrosine and 3-chloro-tyrosine by capillary zone electrophoresis.Journal of Pharmaceutical and Biomedical Analysis,77,83-87. |
| MLA | Ren HX,et al."Measurement of acid dissociation constants and ionic mobilities of 3-nitro-tyrosine and 3-chloro-tyrosine by capillary zone electrophoresis".Journal of Pharmaceutical and Biomedical Analysis 77(2013):83-87. |
入库方式： OAI收割
来源：兰州化学物理研究所
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