Fabrication and characterization of poly(vinyl alcohol)/graphene oxide nanofibrous biocomposite scaffolds
文献类型:期刊论文
作者 | Qi YY(齐园园)1,2; Tai ZX(邰志新)1,3; Sun DF(孙东飞)1,3; Chen JT(陈江涛)1![]() ![]() ![]() ![]() ![]() |
刊名 | Journal of Applied Polymer Science
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出版日期 | 2013 |
卷号 | 127期号:3页码:1885-1894 |
关键词 | poly(vinyl alcohol) graphene oxide nanofiber biocomposite electrospinning |
ISSN号 | 0021-8995 |
通讯作者 | 阎兴斌 ; 刘斌 |
英文摘要 | Nanofibrous biocomposite scaffolds of poly(vinyl alcohol) (PVA) and graphene oxide (GO) were prepared by using electrospinning method. The microstructure, crystallinity, and morphology of the scaffolds were characterized through X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). The mechanical properties were investigated by tensile testing. Moreover, Mouse Osteoblastic Cells (MC3T3-E1) attachment and proliferation on the nanofibrous scaffolds were investigated by MTT [3-(4,5-dimeth-ylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] assay, SEM observation and fluorescence staining. XRD and FTIR results verify the presence of GO in the scaffolds. SEM images show the three-dimensional porous fibrous morphology, and the average diameter of the composite fibers decreases with increasing the content of GO. The mechanical properties of the scaffolds are altered by changing the content of GO as well. The tensile strength and elasticity modulus increase when the content of GO is lower than 1 wt %, but decrease when GO is up to 3 and 5 wt %. MC3T3-E1 cells attach and grow on the surfaces of the scaffolds, and the adding of GO do not affect the cells' viability. Also, MC3T3-E1 cells are likely to spread on the PVA/GO composite scaffolds. Above all, these unique features of the PVA/GO nanofibrous scaffolds prepared by electrospinning would open up a wide variety of future applications in bone tissue engineering and drug delivery systems. |
学科主题 | 材料科学与物理化学 |
收录类别 | SCI |
资助信息 | the National Natural Science Foundation of China, (Grant no.51005225);the Top Hundred Talents Program of Chinese Academy of Sciences |
语种 | 英语 |
WOS记录号 | WOS:000310603100056 |
公开日期 | 2013-12-10 |
源URL | [http://210.77.64.217/handle/362003/4628] ![]() |
专题 | 兰州化学物理研究所_固体润滑国家重点实验室 兰州化学物理研究所_清洁能源化学与材料实验室 |
通讯作者 | Yan XB(阎兴斌); Yan XB(阎兴斌) |
作者单位 | 1.Chinese Acad Sci, State Key Lab Solid Lubricat, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China 2.Lanzhou Univ, Sch Stomatol, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100080, Peoples R China |
推荐引用方式 GB/T 7714 | Qi YY,Tai ZX,Sun DF,et al. Fabrication and characterization of poly(vinyl alcohol)/graphene oxide nanofibrous biocomposite scaffolds[J]. Journal of Applied Polymer Science,2013,127(3):1885-1894. |
APA | Qi YY.,Tai ZX.,Sun DF.,Chen JT.,Ma HB.,...&阎兴斌.(2013).Fabrication and characterization of poly(vinyl alcohol)/graphene oxide nanofibrous biocomposite scaffolds.Journal of Applied Polymer Science,127(3),1885-1894. |
MLA | Qi YY,et al."Fabrication and characterization of poly(vinyl alcohol)/graphene oxide nanofibrous biocomposite scaffolds".Journal of Applied Polymer Science 127.3(2013):1885-1894. |
入库方式: OAI收割
来源:兰州化学物理研究所
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